1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-

Base Information

Chemical Name:1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-
CAS No.:87545-11-7
Molecular Formula:C₁₈H₁₈N₂O₃
Molecular Weight:310.353
Hs Code.:

Synonyms:1-[3-(2-Hydroxy-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazol-1-yl]-ethanone;

Suppliers and Price of 1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-

Chemical Property:

PSA：62.13000
LogP:2.47190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-

There total 5 articles about 1H-Pyrazole, 1-acetyl-4,5-dihydro-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 3327-24-0
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

: 64-19-7,77671-22-8
acetic acid

: 87545-11-7
1-acetyl-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-2-pyrazoline

Guidance literature:: With hydrazine hydrate; for 6h; Reflux;
DOI:10.1021/acs.jmedchem.1c01349

Reference yield: 71.0%

: 64-19-7,77671-22-8
acetic acid

: 55370-75-7
3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole

: 87545-11-7
1-acetyl-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-2-pyrazoline

Guidance literature:: Heating;

Reference yield:

: 3327-24-0
1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one

: 87545-11-7
1-acetyl-3-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-2-pyrazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / hydrazine hydrate / ethanol / Heating

2: 71 percent / Heating

With hydrazine hydrate; In ethanol;