Imidazo[1,2-a]pyrazine-2-methanol

Base Information

• Chemical Name: Imidazo[1,2-a]pyrazine-2-methanol
• CAS No.: 87597-28-2
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.152
• Mol file: 87597-28-2.mol

Synonyms:2-(hydroxymethyl)imidazo[1,2-a]pyrazine;Imidazo[1,2-a]pyrazine-2-methanol;

Chemical Property of Imidazo[1,2-a]pyrazine-2-methanol

Chemical Property:

• PKA: 13.24±0.10(Predicted)
• PSA: 50.42000
• Density: 1.41±0.1 g/cm3(Predicted)
• LogP: 0.22160

Purity/Quality:

99% ^*data from raw suppliers

Imidazo[1,2-a]pyrazin-2-ylmethanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Imidazo[1,2-a]pyrazine-2-methanol

There total 1 articles about Imidazo[1,2-a]pyrazine-2-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-chloromethylimidazo[1,2-a]pyrazine (57937-60-7) → 2-(hydroxymethyl)imidazo[1,2-a]pyrazine (87597-28-2)

Guidance literature:

With sodium hydrogencarbonate; for 1h; Heating;

DOI:10.1021/jm00368a018

upstream raw materials:

2-chloromethylimidazo[1,2-a]pyrazine

Refernces