Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester
CAS No.:876191-29-6
Molecular Formula:C₃₂H₃₈FN₅O₄S
Molecular Weight:607.749
Hs Code.:

Carbamic acid,
[3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[
5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-,
1,1-dimethylethyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester

There total 10 articles about Carbamic acid, [3-[[1-[5-[(3-fluorophenyl)methyl]-4,5-dihydro-3-methyl-4-oxoisothiazolo[ 5,4-d]pyrimidin-6-yl]propyl](4-methylbenzoyl)amino]propyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 876191-28-5
tert-butyl N-[3-[1-[5-[(3-fluorophenyl)methyl]-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl]propylamino]propyl]carbamate

: 874-60-2
4-methyl-benzoyl chloride

: 876191-29-6,876306-95-5
tert-butyl N-[3-[1-[5-[(3-fluorophenyl)methyl]-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl]propyl-(4-methylbenzoyl)amino]propyl]carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 25 ℃; for 0.5h;
DOI:10.1021/jm200629m

Reference yield:

: 162702-06-9
N-(4-cyano-3-methyl-1,2-thiazol-5-yl)butanamide

: 876191-29-6,876306-95-5
tert-butyl N-[3-[1-[5-[(3-fluorophenyl)methyl]-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl]propyl-(4-methylbenzoyl)amino]propyl]carbamate

Guidance literature:: Multi-step reaction with 6 steps

1: ammonium hydroxide; dihydrogen peroxide / water / 16 h / 60 °C

2: ammonium hydroxide / water / 4 h / 140 °C

3: potassium carbonate / N,N-dimethyl-formamide / 16 h / 25 °C

4: bromine; sodium acetate; acetic acid / 0.33 h / 100 °C

5: N-ethyl-N,N-diisopropylamine / ethanol / 16 h / Reflux

6: triethylamine / dichloromethane / 0.5 h / 25 °C

With ammonium hydroxide; dihydrogen peroxide; bromine; sodium acetate; potassium carbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm200629m

Reference yield:

: 162702-38-7
5-(butanoylamino)-3-methyl-1,2-thiazole-4-carboxamide

: 876191-29-6,876306-95-5
tert-butyl N-[3-[1-[5-[(3-fluorophenyl)methyl]-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl]propyl-(4-methylbenzoyl)amino]propyl]carbamate

Guidance literature:: Multi-step reaction with 5 steps

1: ammonium hydroxide / water / 4 h / 140 °C

2: potassium carbonate / N,N-dimethyl-formamide / 16 h / 25 °C

3: bromine; sodium acetate; acetic acid / 0.33 h / 100 °C

4: N-ethyl-N,N-diisopropylamine / ethanol / 16 h / Reflux

5: triethylamine / dichloromethane / 0.5 h / 25 °C

With ammonium hydroxide; bromine; sodium acetate; potassium carbonate; acetic acid; triethylamine; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm200629m