5-(4-Methoxyphenyl)furan-3-carboxylic acid

Base Information

Chemical Name:5-(4-Methoxyphenyl)furan-3-carboxylic acid
CAS No.:87645-58-7
Molecular Formula:C₁₂H₁₀O₄
Molecular Weight:218.209
Hs Code.:
DSSTox Substance ID:DTXSID40518053
Wikidata:Q82380452

Synonyms:5-(4-Methoxyphenyl)furan-3-carboxylic acid;Nurr1 agonist 4;87645-58-7;DTXSID40518053;AKOS022652746;HY-149867;CS-0867254

Suppliers and Price of 5-(4-Methoxyphenyl)furan-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-Methoxyphenyl)furan-3-carboxylic acid

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:218.05790880
Heavy Atom Count:16
Complexity:245

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC(=CO2)C(=O)O

Technology Process of 5-(4-Methoxyphenyl)furan-3-carboxylic acid

There total 2 articles about 5-(4-Methoxyphenyl)furan-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 87645-55-4
2-(p-Anisyl)-3,4-bis(carboxy)furan

: 87645-58-7
2-(p-Anisyl)furan-4-carboxylic acid

Guidance literature:: at 180 - 200 ℃;
DOI:10.1007/BF01150722

Reference yield:

: 82577-49-9
dimethyl 2-(4-methoxyphenyl)furan-3,4-dicarboxylate

: 87645-58-7
2-(p-Anisyl)furan-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / 30percent aq. NaOH / 4 h / Heating

2: 70 percent / 180 - 200 °C

With sodium hydroxide;
DOI:10.1007/BF01150722

Reference yield:

: 1220701-21-2
C₁₆H₁₈N₆O

: 87645-58-7
2-(p-Anisyl)furan-4-carboxylic acid

: 1220701-34-7
C₂₈H₂₆N₆O₄

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2010.01.064