2-chloro-5-(MethoxyMethoxy)pyridine

Base Information

• Chemical Name: 2-chloro-5-(MethoxyMethoxy)pyridine
• CAS No.: 877133-56-7
• Molecular Formula: C7H8ClNO2
• Molecular Weight: 173.599
• Hs Code.: 2933399990
• Mol file: 877133-56-7.mol

Synonyms:2-chloro-5-methoxyindole;2-chloro-5-methoxymethoxy-pyridine;1H-Indole,2-chloro-5-methoxy;

Chemical Property of 2-chloro-5-(MethoxyMethoxy)pyridine

Chemical Property:

• PSA: 31.35000
• LogP: 1.71770
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-5-(methoxymethoxy)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-5-(MethoxyMethoxy)pyridine

There total 3 articles about 2-chloro-5-(MethoxyMethoxy)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-chloropyridine-3-ol (41288-96-4) + bromethyl methyl ether (13057-17-5) → 2-chloro-5-(methoxymethoxy)pyridine (877133-56-7)

Guidance literature:

6-chloropyridine-3-ol; With sodium hydride; In N,N-dimethyl-formamide; at 5 ℃; for 1h; Inert atmosphere;

bromethyl methyl ether; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 89.0%

6-chloropyridine-3-ol (41288-96-4) + chloromethyl methyl ether (107-30-2) → 2-chloro-5-(methoxymethoxy)pyridine (877133-56-7)

Guidance literature:

6-chloropyridine-3-ol; chloromethyl methyl ether; With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 0.25h; Cooling with ice;

With sodium hydrogensulfite; In water; for 0.666667h; Cooling with ice;

Reference yield: 57.0%

→ 2-chloro-5-(methoxymethoxy)pyridine (877133-56-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1.08333h; Inert atmosphere;

In N,N-dimethyl-formamide; at 0 - 20 ℃; for 17h; Inert atmosphere;

upstream raw materials:

6-chloropyridine-3-ol

chloromethyl methyl ether

bromethyl methyl ether

Downstream raw materials:

4-(5-methoxymethoxypyridin-2-yl)piperazine-1-carboxylic acid benzyl ester

4-(5-hydroxypyridin-2-yl)piperazine-1-carboxylic acid benzyl ester

2-chloro-4-iodo-5-(methoxymethoxy)pyridine

6-chloro-4-iodo-pyridin-3-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 877133-56-7 2-chloro-5-(MethoxyMethoxy)pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send