2-chloro-5-hydroxyisonicotinaldehyde

Base Information

Chemical Name:2-chloro-5-hydroxyisonicotinaldehyde
CAS No.:1060804-53-6
Molecular Formula:C6H4ClNO2
Molecular Weight:157.55400
Hs Code.:2933399090
Mol file:1060804-53-6.mol

Synonyms:2-chloro-5-hydroxyisonicotinaldehyde;2-CHLORO-5-HYDROXYPYRIDINE-4-CARBOXALDEHYDE;2-CHLORO-5-HYDROXY-PYRIDINE-4-CARBALDEHYDE;

Suppliers and Price of 2-chloro-5-hydroxyisonicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-5-hydroxyisonicotinaldehyde 98%
250mg
$ 233.00

Crysdot
2-Chloro-5-hydroxyisonicotinaldehyde 98%
1g
$ 581.00

Crysdot
2-Chloro-5-hydroxyisonicotinaldehyde 98%
5g
$ 1634.00

Chemenu
2-chloro-5-hydroxyisonicotinaldehyde 98%
5g
$ 1543.00

Chemenu
2-chloro-5-hydroxyisonicotinaldehyde 98%
1g
$ 549.00

Apolloscientific
2-Chloro-5-hydroxyisonicotinaldehyde 97%
250mg
$ 181.00

Apolloscientific
2-Chloro-5-hydroxyisonicotinaldehyde 97%
100mg
$ 114.00

Alichem
2-Chloro-5-hydroxyisonicotinaldehyde
1g
$ 779.09

AK Scientific
2-Chloro-5-hydroxyisonicotinaldehyde
5g
$ 2453.00

AK Scientific
2-Chloro-5-hydroxyisonicotinaldehyde
100mg
$ 247.00

Total 46 raw suppliers

Chemical Property of 2-chloro-5-hydroxyisonicotinaldehyde

Chemical Property:

Boiling Point:353.3±37.0 °C(Predicted)
PKA:6.71±0.10(Predicted)
PSA：50.19000
Density:1.504±0.06 g/cm3(Predicted)
LogP:1.25310
Storage Temp.:Inert atmosphere,Room Temperature

Purity/Quality:

98+% ^*data from raw suppliers

2-Chloro-5-hydroxyisonicotinaldehyde 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-chloro-5-hydroxyisonicotinaldehyde

There total 3 articles about 2-chloro-5-hydroxyisonicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1282516-32-8
2-chloro-5-(methoxymethoxy)pyridine-4-carbaldehyde

: 1060804-53-6
2-chloro-5-hydroxypyridine-4-carbaldehyde

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; water; at 20 - 60 ℃; for 19h;

Reference yield:

: 877133-56-7
2-chloro-5-(methoxymethoxy)pyridine

: 1060804-53-6
2-chloro-5-hydroxypyridine-4-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: tert.-butyl lithium / tetrahydrofuran; pentane / 0.33 h / -78 °C / Inert atmosphere

1.2: 0.5 h / -80 - -70 °C / Inert atmosphere

2.1: hydrogenchloride / tetrahydrofuran; water / 1 h / 60 °C

With hydrogenchloride; tert.-butyl lithium; In tetrahydrofuran; water; pentane;

Reference yield:

: 41288-96-4
6-chloropyridine-3-ol

: 1060804-53-6
2-chloro-5-hydroxypyridine-4-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere

1.2: 2 h / 10 - 20 °C / Inert atmosphere

2.1: tert.-butyl lithium / tetrahydrofuran; pentane / 0.33 h / -78 °C / Inert atmosphere

2.2: 0.5 h / -80 - -70 °C / Inert atmosphere

3.1: hydrogenchloride / tetrahydrofuran; water / 1 h / 60 °C

With hydrogenchloride; tert.-butyl lithium; sodium hydride; In tetrahydrofuran; water; N,N-dimethyl-formamide; pentane;