N-Benzoyl-2'-O-oxolan-2-ylcytidine

Base Information

Chemical Name:N-Benzoyl-2'-O-oxolan-2-ylcytidine
CAS No.:87865-87-0
Molecular Formula:C20H23N3O7
Molecular Weight:417.419
Hs Code.:
DSSTox Substance ID:DTXSID80560637

Synonyms:N-Benzoyl-2'-O-oxolan-2-ylcytidine;87865-87-0;SCHEMBL7075409;DTXSID80560637

Suppliers and Price of N-Benzoyl-2'-O-oxolan-2-ylcytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Benzoyl-2'-O-oxolan-2-ylcytidine

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:417.15360008
Heavy Atom Count:30
Complexity:707

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(OC1)OC2C(C(OC2N3C=CC(=NC3=O)NC(=O)C4=CC=CC=C4)CO)O
Isomeric SMILES:C1CC(OC1)O[C@@H]2[C@@H]([C@H](O[C@H]2N3C=CC(=NC3=O)NC(=O)C4=CC=CC=C4)CO)O

Technology Process of N-Benzoyl-2'-O-oxolan-2-ylcytidine

There total 5 articles about N-Benzoyl-2'-O-oxolan-2-ylcytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 87865-80-3
N⁴-benzoyl-2'-O-(tetrahydrofuran-2-yl)-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)cytidine

: 87865-87-0
syn-N⁴-benzoyl-2'-O-(tetrahydrofuran-2-yl)cytidine

: 87865-84-7
anti-N⁴-benzoyl-2'-O-(tetrahydrofuran-2-yl)cytidine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran;
DOI:10.1002/hlca.200790034

Reference yield:

: 98-88-4
benzoyl chloride

: 87865-87-0
syn-N⁴-benzoyl-2'-O-(tetrahydrofuran-2-yl)cytidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: chlorotrimethylsilane / pyridine

1.2: pyridine

1.3: 94 percent / NH₄OH

2.1: 94 percent / pyridine

3.1: 97 percent / TsOH / tetrahydrofuran / 3 h / 0 °C

4.1: 41 percent / Bu₄NF / tetrahydrofuran

With chloro-trimethyl-silane; tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine;
DOI:10.1002/hlca.200790034

Reference yield:

: 13089-48-0
N₄-benzoylcytidine

: 87865-87-0
syn-N⁴-benzoyl-2'-O-(tetrahydrofuran-2-yl)cytidine

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / pyridine

2: 97 percent / TsOH / tetrahydrofuran / 3 h / 0 °C

3: 41 percent / Bu₄NF / tetrahydrofuran

With tetrabutyl ammonium fluoride; toluene-4-sulfonic acid; In tetrahydrofuran; pyridine;
DOI:10.1002/hlca.200790034