2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide

Base Information

Chemical Name:2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide
CAS No.:87975-68-6
Molecular Formula:C19H30N2O3S
Molecular Weight:366.525
Hs Code.:
DSSTox Substance ID:DTXSID20579440

Synonyms:87975-68-6;DTXSID20579440;2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide

Suppliers and Price of 2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:366.19771400
Heavy Atom Count:25
Complexity:517

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1(C(O1)C2=CC=CC=C2)CNC3CCCCC3

Technology Process of 2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide

There total 4 articles about 2-[(Cyclohexylamino)methyl]-N,N-diethyl-3-phenyloxirane-2-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 87975-27-7
1-Bromo-2-cyclohexylamino-ethanesulfonic acid diethylamide

: 100-52-7
benzaldehyde

: 87975-68-6
2-Cyclohexylaminomethyl-3-phenyl-oxirane-2-sulfonic acid diethylamide

Guidance literature:: With potassium tert-butylate; In diethyl ether; tert-butyl alcohol; for 24h; Ambient temperature;
DOI:10.1055/s-1983-30527

Reference yield:

: 87975-61-9
1,2-dibromoethane-1-diethylsulfonamide

: 87975-68-6
2-Cyclohexylaminomethyl-3-phenyl-oxirane-2-sulfonic acid diethylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / triethylamine / benzene / 24 h / Ambient temperature

2: 51 percent / benzene / 24 h / Ambient temperature

3: 71 percent / t-C₄H₉OK / 2-methyl-propan-2-ol; diethyl ether / 24 h / Ambient temperature

With potassium tert-butylate; triethylamine; In diethyl ether; tert-butyl alcohol; benzene;
DOI:10.1055/s-1983-30527

Reference yield:

: 7700-08-5
N,N-diethylethene-sulfonamide

: 87975-68-6
2-Cyclohexylaminomethyl-3-phenyl-oxirane-2-sulfonic acid diethylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / Br₂ / CCl₄ / 48 h / Ambient temperature

2: 75 percent / triethylamine / benzene / 24 h / Ambient temperature

3: 51 percent / benzene / 24 h / Ambient temperature

4: 71 percent / t-C₄H₉OK / 2-methyl-propan-2-ol; diethyl ether / 24 h / Ambient temperature

With potassium tert-butylate; bromine; triethylamine; In tetrachloromethane; diethyl ether; tert-butyl alcohol; benzene;
DOI:10.1055/s-1983-30527