n,n-Bis(2-furylmethyl)amine

Base Information

• Chemical Name: n,n-Bis(2-furylmethyl)amine
• CAS No.: 18240-50-1
• Molecular Formula: C10H11 N O2
• Molecular Weight: 177.203
• Hs Code.: 2932190090
• European Community (EC) Number: 856-729-7
• DSSTox Substance ID: DTXSID20339602
• Nikkaji Number: J2.647.761A
• Wikidata: Q82108752
• Mol file: 18240-50-1.mol

Synonyms:n,n-bis(2-furylmethyl)amine;18240-50-1;Bis-furan-2-ylmethyl-amine;1-(furan-2-yl)-N-(furan-2-ylmethyl)methanamine;Bis(furan-2-ylmethyl)amine;bis[(furan-2-yl)methyl]amine;1-(2-furyl)-n-(2-furylmethyl)methanamine;difurfurylamine;Di-furfurylamin;difurfuryl-amine;Oprea1_786065;SCHEMBL843371;DTXSID20339602;BBL018635;MFCD00457144;STK171619;AKOS000264249;N,N-BIS-(2-FURYLMETHYL)AMINE;SB61803;2-Furyl-N-(2-furylmethyl)methanamine #;NS-01494;2-Furanmethanamine, N-(2-furanylmethyl)-;CS-0308292;EN300-11406;Z57046217

Chemical Property of n,n-Bis(2-furylmethyl)amine

Chemical Property:

• Vapor Pressure: 0.024mmHg at 25°C
• Refractive Index: 1.5168
• Boiling Point: 248.7°Cat760mmHg
• Flash Point: 104.2°C
• PSA: 38.31000
• Density: 1.126g/cm³
• LogP: 2.55330
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 177.078978594
• Heavy Atom Count: 13
• Complexity: 136

Purity/Quality:

98%min ^*data from raw suppliers

Bis(furan-2-ylmethyl)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)CNCC2=CC=CO2

Technology Process of n,n-Bis(2-furylmethyl)amine

There total 53 articles about n,n-Bis(2-furylmethyl)amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.7%

furfural (98-01-1) → bis((furan-2-yl)methyl)amine (18240-50-1) + furan-2-ylmethanamine (617-89-0)

Guidance literature:

With ammonium hydroxide; 5% rhodium on activated aluminium oxide; hydrogen; at 80 ℃; for 3h; under 15001.5 Torr; Reagent/catalyst; Temperature; Pressure; Autoclave;

Reference yield: 17.2%

furfural (98-01-1) → N-furfurylidenefurfurylamine (19377-82-3) + bis((furan-2-yl)methyl)amine (18240-50-1) + furan-2-ylmethanamine (617-89-0)

Guidance literature:

With ammonium hydroxide; hydrogen; In methanol; at 90 ℃; for 2h; under 11251.1 Torr; Autoclave; Sealed tube;

DOI:10.1039/d1gc01275d

Reference yield: 6.6%

furfural (98-01-1) + ammonium formate (16712-16-6,64165-14-6,65387-22-6,70179-79-2,540-69-2) → bis((furan-2-yl)methyl)amine (18240-50-1) + furan-2-ylmethanamine (617-89-0) + 2,4,5-tris(furan-2-yl)-1H-imidazole (92438-23-8) + N,N-bis(furan-2-methyl)formamide + N-(furan-2-ylmethyl)formamide (72693-10-8)

Guidance literature:

With formamide; In tetrahydrofuran; at 100 ℃; for 12h; Reagent/catalyst; Temperature; Catalytic behavior; Sealed tube;

DOI:10.1002/cctc.202100977

upstream raw materials:

furfural

2-furancarbonitrile

2-furaldehyde oxime

hydrofuramide

Downstream raw materials:

N-benzyl-1-(furan-2-yl)-N-(furan-2-ylmethyl)methanamine

bis(furan-2-ylmethyl)(4-methoxybenzyl)amine

2-(furylmethyl)-1-oxo-1,2,3,6,7,7a-hexahydro-3a,6-epoxyisoindole-7-carboxylic acid

sulfanilic acid difurfurylamide