N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide
CAS No.:87995-68-4
Molecular Formula:C14H14BrNO2S
Molecular Weight:340.241
Hs Code.:
DSSTox Substance ID:DTXSID10409065
Nikkaji Number:J478.851F
Wikidata:Q82214732

Synonyms:N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide;87995-68-4;DTXSID10409065;AKOS000197177;T6557516;Z45699846

Suppliers and Price of N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:338.99286
Heavy Atom Count:19
Complexity:385

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2=C(C=C(C=C2)C)Br

Technology Process of N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

There total 5 articles about N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-bromo-p-toluidine: 583-68-6
2-bromo-p-toluidine

: 98-59-9
p-toluenesulfonyl chloride

: 87995-68-4
N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; Cooling;
DOI:10.1021/ol501246f

Reference yield: 17.0%

: 594-19-4
tert.-butyl lithium

: 87995-69-5
N-(2-Brom-4-methylphenyl)-4-methyl-N-(4-methylphenylsulfonyl)benzamid

: 87995-68-4
N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

: 99-94-5
p-Toluic acid

: 87995-70-8
4-Methyl-N-<4-methyl-2-(4-methylbenzoyl)phenyl>benzolsulfonamid

: 87995-71-9
N-<2-<1-Hydroxy-2,2-dimethyl-1-(4-methylphenyl)propyl>-4-methylphenyl>-4-methylbenzolsulfonamid

Guidance literature:: With lithium perchlorate; In tetrahydrofuran; pentane; at -100 ℃; Product distribution; var. on concentration on tBuLi;

Reference yield:

: 87995-69-5
N-(2-Brom-4-methylphenyl)-4-methyl-N-(4-methylphenylsulfonyl)benzamid

: 87995-68-4
N-(2-bromo-4-methylphenyl)-4-methylbenzenesulfonamide

: 99-94-5
p-Toluic acid

: 87995-70-8
4-Methyl-N-<4-methyl-2-(4-methylbenzoyl)phenyl>benzolsulfonamid

Guidance literature:: With tert.-butyl lithium; lithium perchlorate; ammonium chloride; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, pentane, -100 deg C, 2) THF, pentane, r.t.;