Benzaldehyde, 5-methoxy-2,3,4-tris(phenylmethoxy)-

Base Information

• Chemical Name: Benzaldehyde, 5-methoxy-2,3,4-tris(phenylmethoxy)-
• CAS No.: 87997-32-8
• Molecular Formula: C29H26O5
• Molecular Weight: 454.522
• Mol file: 87997-32-8.mol

Synonyms:

Chemical Property of Benzaldehyde, 5-methoxy-2,3,4-tris(phenylmethoxy)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzaldehyde, 5-methoxy-2,3,4-tris(phenylmethoxy)-

There total 6 articles about Benzaldehyde, 5-methoxy-2,3,4-tris(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2,3,4-trihydroxy-5-methoxy-benzaldehyde (87997-31-7) + benzyl bromide (100-39-0) → 2,3,4-tribenzyloxy-5-methoxybenzaldehyde (87997-32-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 24h; under vacuum;

Reference yield:

1,2,3-tris-benzyloxybenzene (55020-64-9) → 2,3,4-tribenzyloxy-5-methoxybenzaldehyde (87997-32-8)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) POCl₃ / 1.) RT, 2 h; 2.) chlorobenzene, 60 deg C, 3 h

2: 95 percent / 98percent formic acid, 30percent hydrogen peroxide / CH₂Cl₂ / 2.5 h

3: 89 percent / K₂CO₃ / acetone / 6 h / Heating

4: 73 percent / H₂ / Pd/C / diethyl ether; methanol

5: 6.8 g / HCl gas / diethyl ether

6: 84 percent / K₂CO₃ / dimethylformamide / 24 h / under vacuum

With hydrogenchloride; formic acid; hydrogen; dihydrogen peroxide; potassium carbonate; trichlorophosphate; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone;

Reference yield:

2,3,4-tris(benzyloxy)benzaldehyde (27916-67-2) → 2,3,4-tribenzyloxy-5-methoxybenzaldehyde (87997-32-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 95 percent / 98percent formic acid, 30percent hydrogen peroxide / CH₂Cl₂ / 2.5 h

2: 89 percent / K₂CO₃ / acetone / 6 h / Heating

3: 73 percent / H₂ / Pd/C / diethyl ether; methanol

4: 6.8 g / HCl gas / diethyl ether

5: 84 percent / K₂CO₃ / dimethylformamide / 24 h / under vacuum

With hydrogenchloride; formic acid; hydrogen; dihydrogen peroxide; potassium carbonate; palladium on activated charcoal; In methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone;

upstream raw materials:

2,3,4-trihydroxy-5-methoxy-benzaldehyde

benzyl bromide

1,2,3-tris-benzyloxybenzene

2,3,4-tris(benzyloxy)benzaldehyde

Downstream raw materials:

2'-hydroxy-4',5-dimethoxy-2,3,3',4-tetrabenzyloxychalcone