2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Base Information

Chemical Name:2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid
CAS No.:96928-28-8
Molecular Formula:C₁₉H₁₈N₂O₃S
Molecular Weight:354.43
Hs Code.:
DSSTox Substance ID:DTXSID60914250

Synonyms:BRN 5623173;2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid;96928-28-8;Propanoic acid, 2-(4-(2-((4-methylphenyl)amino)-4-thiazolyl)phenoxy)-;DTXSID60914250;LS-121547;2-{4-[2-(4-Methylanilino)-1,3-thiazol-4-yl]phenoxy}propanoic acid

Suppliers and Price of 2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

Chemical Property:

Vapor Pressure:1.94E-13mmHg at 25°C
Boiling Point:561.3°Cat760mmHg
Flash Point:293.3°C
Density:1.304g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:354.10381361
Heavy Atom Count:25
Complexity:434

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC2=NC(=CS2)C3=CC=C(C=C3)OC(C)C(=O)O

Technology Process of 2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid

There total 4 articles about 2-(4-(2-((4-Methylphenyl)amino)-4-thiazolyl)phenoxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 96928-19-7
2-[4-(2-p-Tolylamino-thiazol-4-yl)-phenoxy]-propionic acid ethyl ester

: 96928-28-8
2-[4-(2-p-Tolylamino-thiazol-4-yl)-phenoxy]-propionic acid

Guidance literature:: With sulfuric acid; Heating;

Reference yield:

: 91143-71-4
(RS)-2-(4-acetylphenoxy)propionic acid

: 96928-28-8
2-[4-(2-p-Tolylamino-thiazol-4-yl)-phenoxy]-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 35.4 percent / conc. H₂SO₄ / 6 h / Heating

2: Br₂, gl. acetic acid / 0.5 h / 0 °C

3: 60 percent / ethanol / Heating

4: 58 percent / 20percent aq. H₂SO₄ / Heating

With sulfuric acid; bromine; acetic acid; In ethanol;

Reference yield:

: 96928-09-5
ethyl 2-(4-acetylphenoxy)-propanoate

: 96928-28-8
2-[4-(2-p-Tolylamino-thiazol-4-yl)-phenoxy]-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Br₂, gl. acetic acid / 0.5 h / 0 °C

2: 60 percent / ethanol / Heating

3: 58 percent / 20percent aq. H₂SO₄ / Heating

With sulfuric acid; bromine; acetic acid; In ethanol;