5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Base Information

Chemical Name:5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione
CAS No.:88048-67-3
Molecular Formula:C12H11IN2O3
Molecular Weight:358.135
Hs Code.:
DSSTox Substance ID:DTXSID20521969
Wikidata:Q82386847

Synonyms:88048-67-3;DTXSID20521969;5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Suppliers and Price of 5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:357.98144
Heavy Atom Count:18
Complexity:377

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(C(=O)NC(=O)NC1=O)C2=CC(=CC=C2)I

Technology Process of 5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione

There total 3 articles about 5-Ethyl-5-(3-iodophenyl)pyrimidine-2,4,6(1H,3H,5H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 88048-65-1
diethyl 2-ethyl-2-(meta-iodophenyl)malonate

: 57-13-6
urea

: 88048-66-2
2-(meta-iodophenyl)butyric acid

: 88048-67-3
5-ethyl-5-(meta-iodophenyl)barbituric acid

Guidance literature:: With C₂H₆O*Na⁽¹⁺⁾; In ethanol; at 82 ℃; for 20h;
DOI:10.1002/jhet.5570200446

Reference yield: 30.0%

: 88048-65-1
diethyl 2-ethyl-2-(meta-iodophenyl)malonate

: 88048-66-2
2-(meta-iodophenyl)butyric acid

: 88048-67-3
5-ethyl-5-(meta-iodophenyl)barbituric acid

Guidance literature:: With C₂H₆O*Na⁽¹⁺⁾; urea; In ethanol; at 82 ℃; for 20h;
DOI:10.1002/jhet.5570200446

Reference yield:

: 76-67-5
diethyl ethyl(phenyl)malonate

: 88048-67-3
5-ethyl-5-(meta-iodophenyl)barbituric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) thalium(III) trifluoroacetate, 2.) aq. KI

2: NaH

With sodium hydride; potassium iodide; thallium(III) trifluoroacetate;