2-Chloro-3-(4-methoxyphenyl)pyrazine

Base Information

Chemical Name:2-Chloro-3-(4-methoxyphenyl)pyrazine
CAS No.:88066-88-0
Molecular Formula:C11H9ClN2O
Molecular Weight:220.658
Hs Code.:
DSSTox Substance ID:DTXSID70526949
Wikidata:Q82395940

Synonyms:2-Chloro-3-(4-methoxyphenyl)pyrazine;88066-88-0;SCHEMBL3322656;DTXSID70526949;GCPMYPGHEQLFFI-UHFFFAOYSA-N;2-chloro-3-p-methoxyphenylpyrazine;AKOS014986635;2-chloro-3-(4-methoxyphenyl)-pyrazine

Suppliers and Price of 2-Chloro-3-(4-methoxyphenyl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Chloro-3-(4-methoxyphenyl)pyrazine

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:220.0403406
Heavy Atom Count:15
Complexity:195

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=CN=C2Cl

Technology Process of 2-Chloro-3-(4-methoxyphenyl)pyrazine

There total 2 articles about 2-Chloro-3-(4-methoxyphenyl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 4858-85-9
2,3-dichloropyrazine

: 5720-07-0
4-methoxyphenylboronic acid

: 88066-88-0
2-chloro-3-(4-methoxyphenyl)pyrazine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; Reflux; Inert atmosphere;
DOI:10.1021/acs.orglett.9b03214

Reference yield: 54.0%

: 88066-88-0
2-chloro-3-(4-methoxyphenyl)pyrazine

Guidance literature:

Reference yield: 78.0%

: 88066-88-0
2-chloro-3-(4-methoxyphenyl)pyrazine

: 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-cyclohexen-1-one

: 3-(3-(4-methoxyphenyl)pyrazin-2-yl)-2-methylcyclohex-2-en-1-one

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; Reflux; Inert atmosphere;
DOI:10.1021/acs.orglett.9b03214