Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate

Base Information

Chemical Name:Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate
CAS No.:35620-60-1
Molecular Formula:C10H13NO4
Molecular Weight:211.2145
Hs Code.:
NSC Number:173112,124689
DSSTox Substance ID:DTXSID70298619
Mol file:35620-60-1.mol

Synonyms:ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate;35620-60-1;NSC124689;DTXSID70298619;NSC173112;NSC-124689;NSC-173112;1-ethoxycarbonylpyrrolizidine-2,3-dione

Suppliers and Price of Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate

Chemical Property:

Vapor Pressure:0.000435mmHg at 25°C
Boiling Point:315.5°Cat760mmHg
Flash Point:144.6°C
Density:1.3g/cm³
XLogP3:0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:211.08445790
Heavy Atom Count:15
Complexity:325

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1C2CCCN2C(=O)C1=O

Technology Process of Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate

There total 3 articles about Ethyl 2,3-dioxohexahydro-1h-pyrrolizine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 5027-77-0
homoproline ethyl ester acetate

: 95-92-1
oxalic acid diethyl ester

: 35620-60-1
1-carbethoxy-2,3-dioxopyrrolizidine

Guidance literature:: With sodium ethanolate; In ethanol; for 3h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetlet.2017.12.015

Reference yield:

: 4778-25-0
(1H-pyrrol-2-yl)acetic acid ethyl ester

: 35620-60-1
1-carbethoxy-2,3-dioxopyrrolizidine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen; 5% rhodium on activated aluminium oxide / acetic acid / 760.05 Torr

2: sodium ethanolate / ethanol / 3 h / Inert atmosphere; Reflux

With 5% rhodium on activated aluminium oxide; hydrogen; sodium ethanolate; In ethanol; acetic acid;
DOI:10.1016/j.tetlet.2017.12.015