N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide

Base Information

Chemical Name:N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide
CAS No.:88069-44-7
Molecular Formula:C₁₅H₂₁N₃O
Molecular Weight:259.351
Hs Code.:
ChEMBL ID:CHEMBL163987
DSSTox Substance ID:DTXSID50529054
Wikidata:Q82399175

Synonyms:88069-44-7;CHEMBL163987;DTXSID50529054;N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide

Suppliers and Price of N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:259.168462302
Heavy Atom Count:19
Complexity:334

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCCN2C1)CC(=O)NC3=CC=CC=C3N

Technology Process of N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide

There total 2 articles about N-(2-Aminophenyl)-2-(tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-azoniabicyclo[3.3.0]oct-1⁽⁵⁾-ene perchlorate

: 88069-44-7
N-(2-Amino-phenyl)-2-(tetrahydro-pyrrolizin-7a-yl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 5.01 g / ethanol / 8 h / Heating

2: 1.) NaH / 1.) 1,4-dioxane, 100 deg C, 2 h, 2.) 1,4-dioxane, 100 deg C, 2 h

With sodium hydride; In ethanol;
DOI:10.1021/jm00383a005

Reference yield:

: 88069-56-1
ethyl tetrahydro-1H-pyrrolizin-7a(5H)-ylacetate

: 95-54-5
1,2-diamino-benzene

: 88069-44-7
N-(2-Amino-phenyl)-2-(tetrahydro-pyrrolizin-7a-yl)-acetamide

Guidance literature:: With sodium hydride; Multistep reaction; 1.) 1,4-dioxane, 100 deg C, 2 h, 2.) 1,4-dioxane, 100 deg C, 2 h;
DOI:10.1021/jm00383a005