N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine

Base Information

Chemical Name:N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine
CAS No.:88127-66-6
Molecular Formula:C₉H₁₁BrNO₂P
Molecular Weight:276.07
Hs Code.:
DSSTox Substance ID:DTXSID80520054
Wikidata:Q82383665

Synonyms:88127-66-6;N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine;DTXSID80520054

Suppliers and Price of N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine

Chemical Property:

PSA：35.29000
LogP:3.15900
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:274.97108
Heavy Atom Count:14
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C1=CC=CC=C1Br)P2OCCO2

Technology Process of N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine

There total 3 articles about N-(2-Bromophenyl)-N-methyl-1,3,2-dioxaphospholan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 6832-87-7
2-bromo-N-methylaniline

: 822-39-9
2-chloro-1,3,2-dioxaphospholan

: 88127-66-6
(2-Bromo-phenyl)-[1,3,2]dioxaphospholan-2-yl-methyl-amine

Guidance literature:: With TEA; In diethyl ether; 5 h, reflux; 2 d, 20 deg C;

Reference yield:

: 10113-38-9
N-(2-bromophenyl)formamide

: 88127-66-6
(2-Bromo-phenyl)-[1,3,2]dioxaphospholan-2-yl-methyl-amine

Guidance literature:: Multi-step reaction with 3 steps

1: KOH / dimethylsulfoxide / 4 h / Ambient temperature

2: 77 percent / H₂SO₄ / H₂O / 2 h / Heating

3: 51 percent / TEA / diethyl ether / 5 h, reflux; 2 d, 20 deg C

With potassium hydroxide; TEA; sulfuric acid; In diethyl ether; water; dimethyl sulfoxide;

Reference yield:

: 344746-77-6
2-bromo-N-methylformanilide

: 88127-66-6
(2-Bromo-phenyl)-[1,3,2]dioxaphospholan-2-yl-methyl-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / H₂SO₄ / H₂O / 2 h / Heating

2: 51 percent / TEA / diethyl ether / 5 h, reflux; 2 d, 20 deg C

With TEA; sulfuric acid; In diethyl ether; water;