1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

Base Information

Chemical Name:1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole
CAS No.:88138-61-8
Molecular Formula:C12H13N3O3
Molecular Weight:247.254
Hs Code.:
ChEMBL ID:CHEMBL2414447
DSSTox Substance ID:DTXSID60529227
Wikidata:Q82399506

Synonyms:88138-61-8;1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole;CHEMBL2414447;1-[3-(4-nitrophenoxy)propyl]imidazole;SCHEMBL6642525;DTXSID60529227;GYVYWAUONFWZDV-UHFFFAOYSA-N;BDBM50438664;AKOS030653031;4-[3-(Imidazol-1-yl)propoxy]nitrobenzene;EN300-26866621;Z426156554

Suppliers and Price of 1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:247.09569129
Heavy Atom Count:18
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1[N+](=O)[O-])OCCCN2C=CN=C2

Technology Process of 1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

There total 4 articles about 1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 288-32-4
1H-imidazole

: 13094-50-3
1-(3-bromopropoxy)-4-nitrobenzene

: 88138-61-8
1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

Guidance literature:: With potassium carbonate; In acetonitrile; at 80 ℃;
DOI:10.1021/acsinfecdis.0c00855

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 88138-61-8
1-[3-(4-nitrophenoxy)propyl]-1H-Imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 0.5 h / 90 °C / Microwave irradiation

2: triethylamine; tetrabutylammomium bromide / acetonitrile / 0.5 - 45 h / 100 °C / 7757.43 Torr / Microwave irradiation

With tetrabutylammomium bromide; potassium carbonate; triethylamine; In acetone; acetonitrile;
DOI:10.1016/j.bmc.2013.06.040