3-(2-Nitrobenzylidenamino)-2-oxazolidinone

Base Information

• Chemical Name: 3-(2-Nitrobenzylidenamino)-2-oxazolidinone
• CAS No.: 19687-73-1
• Molecular Formula: C10H9 N3 O4
• Molecular Weight: 235.2
• Mol file: 19687-73-1.mol

Synonyms:19687-73-1;2-NP-AOZ;3-(2-Nitrobenzylidenamino)-2-oxazolidinone;2-Oxazolidone, 3-(o-nitrobenzylideneamino)-;3-((2-Nitrobenzylidene)amino)oxazolidin-2-one;3-((o-Nitrophenyl)methyleneamino)-2-oxazolidone;2-Oxazolidone, 3-((2-nitrophenyl)methyleneamino)-;2-Oxazolidone, 3-((o-nitrophenyl)methyleneamino)-;3-[(E)-(2-nitrophenyl)methylideneamino]-1,3-oxazolidin-2-one;C10H9N3O4;(E)-3-((2-nitrobenzylidene)amino)oxazolidin-2-one;OHYXOGZWSSNLON-YRNVUSSQSA-N;MFCD01013510;AKOS015833494;AKOS040757177;AS-7044;HY-136444;LS-100711;CS-0129430;2-NP-AOZ, VETRANAL(TM), analytical standard;A813876;J-012728;2-Oxazolidinone, 3-[[(2-nitrophenyl)methylene]amino]-;3-[(E)-(2-nitrophenyl)methyleneamino]oxazolidin-2-one;3-Amino-2-oxazolidinone, 2-nitrobenzaldehyde derivative;3-[(E)-[(2-nitrophenyl)methylidene]amino]-1,3-oxazolidin-2-one

Chemical Property of 3-(2-Nitrobenzylidenamino)-2-oxazolidinone

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 175-176℃
• Boiling Point: 380.8°Cat760mmHg
• Flash Point: 184.1°C
• PSA: 87.72000
• Density: 1.45g/cm³
• LogP: 1.84200
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly, Heated), Methanol (Slightly)
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 235.05930578
• Heavy Atom Count: 17
• Complexity: 339

Purity/Quality:

97% ^*data from raw suppliers

2-NP-AOZ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1COC(=O)N1N=CC2=CC=CC=C2[N+](=O)[O-]
• Isomeric SMILES: C1COC(=O)N1/N=C/C2=CC=CC=C2[N+](=O)[O-]
• Uses: A derivatized of 3-amino-2-oxazolidone (AOZ, A618570), a metabolite of Furazolidone and Nitrofuran. A derivative of 3-amino-2-oxazolidone (AOZ, A618570), a metabolite of Furazolidone and Nitrofuran. A derivative of 3-amino-2-oxazolidone (AOZ, A618570), a metabolite of Furazolidone and Nitrofuran.Environmental contaminants; Food contaminants; Heat processing contaminants

Technology Process of 3-(2-Nitrobenzylidenamino)-2-oxazolidinone

There total 4 articles about 3-(2-Nitrobenzylidenamino)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-amino-2-oxazolidinone (80-65-9) + 2-nitro-benzaldehyde (552-89-6) → 3<<(2-Nitrophenyl)methylene>amino>-2-oxazolidinone (19687-73-1)

Guidance literature:

With hydrogenchloride; In dimethyl sulfoxide; at 37 ℃; for 20h;

DOI:10.3109/00498259409043272

Reference yield:

2-nitro-benzaldehyde (552-89-6) → 3<<(2-Nitrophenyl)methylene>amino>-2-oxazolidinone (19687-73-1)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. HCl / ethanol

2: PCl₅, POCl₃

3: NaOEt

With hydrogenchloride; phosphorus pentachloride; sodium ethanolate; trichlorophosphate; In ethanol;

Reference yield:

(2-nitro-benzylidene)-hydrazinecarboxylic acid 2-chloro-ethyl ester (19693-50-6) → 3<<(2-Nitrophenyl)methylene>amino>-2-oxazolidinone (19687-73-1)

Guidance literature:

With sodium ethanolate;

upstream raw materials:

(2-nitro-benzylidene)-hydrazinecarboxylic acid 2-chloro-ethyl ester

3-amino-2-oxazolidinone

2-nitro-benzaldehyde

N'-(2-Nitro-benzyliden)-hydrazincarbonsaeure-(2-hydroxy-aethylester)

Downstream raw materials:

3-[2-(2,2-dichloro-acetylamino)-benzylideneamino]-oxazolidin-2-one

3-(2-amino-benzylideneamino)-oxazolidin-2-one