2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene

Base Information

• Chemical Name: 2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene
• CAS No.: 88141-36-0
• Molecular Formula: C16H26Se
• Molecular Weight: 297.342
• DSSTox Substance ID: DTXSID70520644
• Nikkaji Number: J469.300K
• Wikidata: Q82384661
• Mol file: 88141-36-0.mol

Synonyms:2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene;88141-36-0;DTXSID70520644

Chemical Property of 2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 298.11997
• Heavy Atom Count: 17
• Complexity: 202

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1=CC(=C(C(=C1)C(C)C)[Se]C)C(C)C

Technology Process of 2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene

There total 9 articles about 2-(Methylselanyl)-1,3,5-tri(propan-2-yl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

bis(2,4,6-triisopropylphenyl)diselenide (71518-96-2) + methyl iodide (74-88-4) → Methyl 2,4,6-triisopropylphenyl selenide (88141-36-0)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1016/S0040-4039(00)88132-0

Reference yield: 81.0%

(Z)-1-[1,3]dithian-2-yl-4-(2,4,6-triisopropyl-phenylselanyl)-hex-4-en-2-ol (862297-54-9) + methyl iodide (74-88-4) → (Z)-1-[1,3]dithian-2-yl-4-iodo-hex-4-en-2-ol (862297-55-0) + Methyl 2,4,6-triisopropylphenyl selenide (88141-36-0)

Guidance literature:

Multistep reaction;

DOI:10.1016/j.tetlet.2005.05.054 DOI:10.1016/j.tet.2005.12.005

Reference yield:

(E)-2-(1-iodo-propenylselanyl)-1,3,5-triisopropyl-benzene (862133-59-3) → Methyl 2,4,6-triisopropylphenyl selenide (88141-36-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C

1.2: 100 percent / BF₃*OEt₂ / tetrahydrofuran; hexane / 1 h / -78 °C

With n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1016/j.tet.2005.12.005

upstream raw materials:

bis(2,4,6-triisopropylphenyl)diselenide

methyl iodide

dimethyl diselenide

(2,4,6-triisopropylphenyl)magnesium bromide

Downstream raw materials:

methyl 2,4,6-triisopropylphenyl selenoxide