(1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol

Base Information

Chemical Name:(1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol
CAS No.:88141-62-2
Molecular Formula:C₁₉H₂₃NO
Molecular Weight:281.398
Hs Code.:
DSSTox Substance ID:DTXSID60521923

Synonyms:88141-62-2;DTXSID60521923;(1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol

Suppliers and Price of (1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:281.177964357
Heavy Atom Count:21
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NC1CCC(=CC1O)C2=CC3=CC=CC=C3C=C2
Isomeric SMILES:CC(C)N[C@@H]1CCC(=C[C@H]1O)C2=CC3=CC=CC=C3C=C2

Technology Process of (1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol

There total 3 articles about (1R,6R)-3-(Naphthalen-2-yl)-6-[(propan-2-yl)amino]cyclohex-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88141-50-8
N-((1S,2S)-2-Hydroxy-4-naphthalen-2-yl-cyclohex-3-enyl)-acetamide

: 88141-62-2
(1S,6S)-6-Isopropylamino-3-naphthalen-2-yl-cyclohex-2-enol

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / 1.) 10percent NaOH, 2.) 7N HCl-EtOH / ethanol / 20 h / 70 - 80 °C

2: NaBH₃CN / methanol / 72 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; sodium cyanoborohydride; In methanol; ethanol;
DOI:10.1248/cpb.31.2016

Reference yield:

: 88141-46-2
N-(4-Naphthalen-2-yl-2-oxo-cyclohex-3-enyl)-acetamide

: 88141-62-2
(1S,6S)-6-Isopropylamino-3-naphthalen-2-yl-cyclohex-2-enol

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / NaBH₄ / methanol / 0.17 h / Ambient temperature

2: 81 percent / 1.) 10percent NaOH, 2.) 7N HCl-EtOH / ethanol / 20 h / 70 - 80 °C

3: NaBH₃CN / methanol / 72 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; sodium cyanoborohydride; In methanol; ethanol;
DOI:10.1248/cpb.31.2016