Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate

Base Information

Chemical Name:Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate
CAS No.:88147-23-3
Molecular Formula:C₈H₁₀O₄
Molecular Weight:170.165
Hs Code.:
DSSTox Substance ID:DTXSID40542974
Wikidata:Q82419789

Synonyms:88147-23-3;DTXSID40542974;Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate

Suppliers and Price of Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate

Chemical Property:

XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:170.05790880
Heavy Atom Count:12
Complexity:231

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1C(C=CC1=O)O
Isomeric SMILES:COC(=O)C[C@H]1[C@@H](C=CC1=O)O

Technology Process of Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate

There total 1 articles about Methyl [(1S,2R)-2-hydroxy-5-oxocyclopent-3-en-1-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.6%

: 25290-21-5
methyl 3-(furan-2-yl)-3-hydroxypropanoate

: 58293-85-9
methyl 3-(2-furyl)acrylate

: 88147-21-1
2-methoxycarbonylmethyl-4-hydroxy-2-cyclopenten-1-one

: 88147-23-3,92072-27-0,118204-26-5,118204-27-6,120710-62-5
2-methoxycarbonylmethyl-3-hydroxy-4-cyclopenten-1-one

Guidance literature:: With hydrogenchloride; zinc(II) chloride; In 1,4-dioxane; water; for 3h; Product distribution; other cocatalyst (Amberlite IRC-50 cation-exchange resin), other time;

Reference yield:

: 88147-23-3,92072-27-0,118204-26-5,118204-27-6,120710-62-5
2-methoxycarbonylmethyl-3-hydroxy-4-cyclopenten-1-one

: 98451-33-3
2-carboxymethyl-4-p-phenylbenzoyloxy-2-cyclopenten-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 47.6 percent / aluminum oxide / benzene / 17.5 h / 20 °C

2: 50 percent / pyridine / 5 h / 20 °C

3: 79 percent / aq. HCl / dioxane / 4.5 h / Heating

With pyridine; hydrogenchloride; aluminum oxide; In 1,4-dioxane; benzene;

Reference yield:

: 88147-23-3,92072-27-0,118204-26-5,118204-27-6,120710-62-5
2-methoxycarbonylmethyl-3-hydroxy-4-cyclopenten-1-one

: 104314-69-4
2-methoxycarbonylmethyl-4S-benzoyloxy-2-cyclopenten-1-one

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / conc. HCl / H₂O / 1.5 h / 50 °C

2: chloral, Et₃N / ethyl acetate / 24 h / 20 °C

3: 0.011 g / 3N HCl(g) in methanol / 24 h / 20 °C

4: 0.0125 g / pyridine / 6 h / 50 °C

With pyridine; hydrogenchloride; chloral; triethylamine; In water; ethyl acetate;