2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile

Base Information

Chemical Name:2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile
CAS No.:88167-51-5
Molecular Formula:C9H6BrClN2O
Molecular Weight:273.516
Hs Code.:
DSSTox Substance ID:DTXSID80538093
Nikkaji Number:J998.543C
Wikidata:Q82413315

Synonyms:88167-51-5;2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile;2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile;SCHEMBL6478409;DTXSID80538093

Suppliers and Price of 2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:271.93520
Heavy Atom Count:14
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1C#N)N)Cl)C(=O)CBr

Technology Process of 2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile

There total 5 articles about 2-Amino-5-(bromoacetyl)-3-chlorobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 97760-78-6
4'-amino-3'-chloro-5'-cyano-acetophenone

: 88167-51-5
2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile

Guidance literature:: With bromine; In acetic acid; Irradiation;

Reference yield:

: 33720-71-7
4-amino-3-cyanoacetophenone

: 88167-51-5
2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 51.5 percent / Cl₂ / methanol; aq. acetic acid / 0.05 h / 7 °C

2: Br₂ / acetic acid / Irradiation

With bromine; chlorine; In methanol; acetic acid;

Reference yield:

: 99-92-3
p-aminobenzophenone

: 88167-51-5
2-amino-5-(2-bromoacetyl)-3-chlorobenzonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: I₂, CaCO₃ / methanol; H₂O / 80 h / Ambient temperature

2: 52 percent / dimethylformamide / 1.5 h / Heating

3: 51.5 percent / Cl₂ / methanol; aq. acetic acid / 0.05 h / 7 °C

4: Br₂ / acetic acid / Irradiation

With bromine; iodine; chlorine; calcium carbonate; In methanol; water; acetic acid; N,N-dimethyl-formamide;