2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole
CAS No.:88185-06-2
Molecular Formula:C15H11N3O3
Molecular Weight:281.271
Hs Code.:
DSSTox Substance ID:DTXSID70518602
Wikidata:Q82381350

Synonyms:88185-06-2;2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole;DTXSID70518602

Suppliers and Price of 2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:281.08004122
Heavy Atom Count:21
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NN=C(O2)C3=CC=CC=C3[N+](=O)[O-]

Technology Process of 2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole

There total 4 articles about 2-(4-Methylphenyl)-5-(2-nitrophenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 88185-05-1
1-(2-Nitrobenzoyl)-2-(4-methylbenzoyl)-hydrazine

: 88185-06-2
2-(2-Nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; Heating;

Reference yield:

: 3619-22-5
p-toluic hydrazide

: 88185-06-2
2-(2-Nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / pyridine

2: 68 percent / POCl₃ / Heating

With pyridine; trichlorophosphate;

Reference yield:

: 610-14-0
2-nitrobenzyl chloride

: 88185-06-2
2-(2-Nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / pyridine / Ambient temperature

2: 52 percent / POCl₃ / 3 h / Heating

With pyridine; trichlorophosphate;
DOI:10.1055/s-1983-30538