1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole

Base Information

Chemical Name:1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole
CAS No.:88207-50-5
Molecular Formula:C20H14BrNO2S
Molecular Weight:412.307
Hs Code.:
DSSTox Substance ID:DTXSID90527857
Wikidata:Q82397077

Synonyms:3-bromo-2-phenyl-1-(phenylsulfonyl)-1H-indole;88207-50-5;1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole;DTXSID90527857

Suppliers and Price of 1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole

Chemical Property:

XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:410.99286
Heavy Atom Count:25
Complexity:549

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2S(=O)(=O)C4=CC=CC=C4)Br

Technology Process of 1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole

There total 2 articles about 1-(Benzenesulfonyl)-3-bromo-2-phenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 114650-12-3
2-phenyl-1-(phenylsulfonyl)-1H-indole

: 88207-50-5
3-bromo-2-phenyl-1-(phenylsulfonyl)-1H-indole

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/acs.organomet.5b00631

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 40899-71-6
1-benzenesulfonylindole

: 88207-50-5
3-bromo-2-phenyl-1-(phenylsulfonyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

1.3: 12 h / 20 °C / Inert atmosphere

2.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 12 h / 20 °C

With N-Bromosuccinimide; n-butyllithium; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1021/acs.organomet.5b00631