4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one

Base Information

Chemical Name:4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one
CAS No.:88220-44-4
Molecular Formula:C14H9ClN2O2
Molecular Weight:272.691
Hs Code.:
DSSTox Substance ID:DTXSID60521625
Wikidata:Q82386203

Synonyms:88220-44-4;4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one;DTXSID60521625

Suppliers and Price of 4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:272.0352552
Heavy Atom Count:19
Complexity:378

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NC(=O)O2)NC3=CC=C(C=C3)Cl

Technology Process of 4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one

There total 4 articles about 4-(4-Chloroanilino)-2H-1,3-benzoxazin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 88220-36-4
2-<(4-chlorophenyl)aminocarbonyloxy>benzonitrile

: 88220-44-4
4-<(4-chlorophenyl)amino>-2H-1,3-benzoxazin-2-one

Guidance literature:: With triethylamine; In toluene; for 46h; Heating;

Reference yield: 74.0%

: 611-20-1
salicylonitrile

: 104-12-1
p-chlorphenylisocyanate

: 88220-44-4
4-<(4-chlorophenyl)amino>-2H-1,3-benzoxazin-2-one

Guidance literature:: With triethylamine; In toluene; for 6h; Heating;

Reference yield:

: 611-20-1
salicylonitrile

: 88220-44-4
4-<(4-chlorophenyl)amino>-2H-1,3-benzoxazin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / triethylamine / diethyl ether / 0.08 h

2: 75 percent / triethylamine / toluene / 46 h / Heating

With triethylamine; In diethyl ether; toluene;