N-cyclopropyl-4-methylbenzamide

Base Information

Chemical Name:N-cyclopropyl-4-methylbenzamide
CAS No.:88229-12-3
Molecular Formula:C11H13NO
Molecular Weight:175.23
Hs Code.:
DSSTox Substance ID:DTXSID30399575
Wikidata:Q82202216

Synonyms:N-cyclopropyl-4-methylbenzamide;88229-12-3;SCHEMBL241843;DTXSID30399575;AKOS003269224

Suppliers and Price of N-cyclopropyl-4-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of N-cyclopropyl-4-methylbenzamide

Chemical Property:

PSA：29.10000
LogP:2.27810
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:175.099714038
Heavy Atom Count:13
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(=O)NC2CC2

Technology Process of N-cyclopropyl-4-methylbenzamide

There total 3 articles about N-cyclopropyl-4-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 874-60-2
4-methyl-benzoyl chloride

: 765-30-0
Cyclopropylamine

: 88229-12-3
N-cyclopropyl-4-methylbenzamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;
DOI:10.1002/anie.202007864 DOI:10.1021/jacs.1c06700

Reference yield:

: C₁₀H₁₀O₄

: 765-30-0
Cyclopropylamine

: 88229-12-3
N-cyclopropyl-4-methylbenzamide

Guidance literature:: In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.bmcl.2014.12.085

Reference yield:

: 99-94-5
p-Toluic acid

: 88229-12-3
N-cyclopropyl-4-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C / Cooling with ice

2: dichloromethane / 2 h / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2014.12.085