1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-

Base Information

Chemical Name:1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-
CAS No.:88251-66-5
Molecular Formula:C10H6F3N3O2S
Molecular Weight:289.238
Hs Code.:
DSSTox Substance ID:DTXSID50406194
Wikidata:Q82211097

Synonyms:88251-66-5;1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-;2-((2-Nitro-4-(trifluoromethyl)phenyl)thio)-1H-imidazole;DTXSID50406194;AKOS002665549

Suppliers and Price of 1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:289.01328210
Heavy Atom Count:19
Complexity:337

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)[N+](=O)[O-])SC2=NC=CN2

Technology Process of 1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]-

There total 1 articles about 1H-Imidazole, 2-[[2-nitro-4-(trifluoromethyl)phenyl]thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 872-35-5
1,3-dihydro-imidazole-2-thione

: 121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene

: 88251-66-5
2-(2-nitro-4-trifluoromethylphenylthio)imidazole

Guidance literature:: With sodium ethanolate; In ethanol; for 4h; Heating;
DOI:10.1002/jhet.5570200528

Reference yield: 84.3%

: 88251-66-5
2-(2-nitro-4-trifluoromethylphenylthio)imidazole

: 88251-71-2
2-(2-amino-4-trifluoromethylphenylthio)imidazole

Guidance literature:: With hydrogenchloride; tin; In ethanol; for 0.5h; steam bath;
DOI:10.1002/jhet.5570200528

Reference yield:

: 88251-66-5
2-(2-nitro-4-trifluoromethylphenylthio)imidazole

: 88251-83-6
1-<2-(2-imidazolyl)thio-5-trifluoromethylphenyliminocarbonyl>-4-methylpiperazine

Guidance literature:: Multi-step reaction with 3 steps

1: 84.3 percent / Sn, conc.HCl / ethanol / 0.5 h / steam bath

2: 72 percent / CH₂Cl₂ / 3 h / Ambient temperature

3: 100 percent / CH₂Cl₂ / Ambient temperature; overnight

With hydrogenchloride; tin; In ethanol; dichloromethane;
DOI:10.1002/jhet.5570200528