Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-

Base Information

Chemical Name:Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-
CAS No.:88251-71-2
Molecular Formula:C10H8F3N3S
Molecular Weight:259.255
Hs Code.:
DSSTox Substance ID:DTXSID70406196
Wikidata:Q82211100

Synonyms:88251-71-2;Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-;2-((1H-Imidazol-2-yl)thio)-5-(trifluoromethyl)aniline;DTXSID70406196;AKOS002665551

Suppliers and Price of Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:259.03910293
Heavy Atom Count:17
Complexity:262

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)N)SC2=NC=CN2

Technology Process of Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)-

There total 2 articles about Benzenamine, 2-(1H-imidazol-2-ylthio)-5-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.3%

: 88251-66-5
2-(2-nitro-4-trifluoromethylphenylthio)imidazole

: 88251-71-2
2-(2-amino-4-trifluoromethylphenylthio)imidazole

Guidance literature:: With hydrogenchloride; tin; In ethanol; for 0.5h; steam bath;
DOI:10.1002/jhet.5570200528

Reference yield:

: 121-17-5
2-chloro-3-nitro-5-trifluoromethylbenzene

: 88251-71-2
2-(2-amino-4-trifluoromethylphenylthio)imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / NaOC₂H₅ / ethanol / 4 h / Heating

2: 84.3 percent / Sn, conc.HCl / ethanol / 0.5 h / steam bath

With hydrogenchloride; tin; sodium ethanolate; In ethanol;
DOI:10.1002/jhet.5570200528

Reference yield:

: 88251-71-2
2-(2-amino-4-trifluoromethylphenylthio)imidazole

: 88251-83-6
1-<2-(2-imidazolyl)thio-5-trifluoromethylphenyliminocarbonyl>-4-methylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / CH₂Cl₂ / 3 h / Ambient temperature

2: 100 percent / CH₂Cl₂ / Ambient temperature; overnight

In dichloromethane;
DOI:10.1002/jhet.5570200528