4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole

Base Information

Chemical Name:4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole
CAS No.:88264-13-5
Molecular Formula:C23H19NO2S2
Molecular Weight:405.541
Hs Code.:
DSSTox Substance ID:DTXSID90703851
Wikidata:Q82636120

Synonyms:88264-13-5;DTXSID90703851;4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole

Suppliers and Price of 4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole

Chemical Property:

XLogP3:6.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:405.08572120
Heavy Atom Count:28
Complexity:458

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(SC(=N2)SC3=CC=CC=C3)C4=CC=C(C=C4)OC

Technology Process of 4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole

There total 5 articles about 4,5-Bis(4-methoxyphenyl)-2-(phenylsulfanyl)-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 696-62-8
para-iodoanisole

: 1319212-49-1
C₁₆H₁₃NOS₂

: 88264-13-5
4,5-Bis(4-methoxyphenyl)-2-phenylthio-thiazol

Guidance literature:: C₁₆H₁₃NOS₂; With bis(2,2,6,6-tetramethylpiperidinyl)zinc, lithium chloride, magnesium chloride complex; In tetrahydrofuran; at 25 ℃; for 2h; Inert atmosphere;

para-iodoanisole; With (1E,4E)-1,5-diphenylpenta-1,4-dien-3-one palladium(II) complex; trifuran-2-yl-phosphane; In tetrahydrofuran; at 25 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jo201250n

Reference yield: 53.0%

: 1483-73-4
diphenyliodonium bromide

: 43045-26-7
4,5-Bis(4-methoxyphenyl)-thiazol-2-thiol

: 88264-13-5
4,5-Bis(4-methoxyphenyl)-2-phenylthio-thiazol

Guidance literature:: With sodium; In ethanol; Heating;
DOI:10.1002/ardp.19833161108

Reference yield:

: 27895-95-0
2-bromo-1,2-bis(4-methoxyphenyl)ethanone

: 88264-13-5
4,5-Bis(4-methoxyphenyl)-2-phenylthio-thiazol

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / ethanol / 3 h / 60 °C

2: 53 percent / Na / ethanol / Heating

With sodium; In ethanol;
DOI:10.1002/ardp.19833161108