2(3H)-Furanone, dihydro-5-propyl-, (R)-

Base Information

• Chemical Name: 2(3H)-Furanone, dihydro-5-propyl-, (R)-
• CAS No.: 88270-38-6
• Molecular Formula: C7H12O2
• Molecular Weight: 128.171
• Mol file: 88270-38-6.mol

Synonyms:

Chemical Property of 2(3H)-Furanone, dihydro-5-propyl-, (R)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2(3H)-Furanone, dihydro-5-propyl-, (R)-

There total 6 articles about 2(3H)-Furanone, dihydro-5-propyl-, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3S)-3-propyl-2-oxiranemethanol (89321-71-1) → (R)-5-propyl-dihydrofuran-2(3H)-one (88270-38-6)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) sodium metaperiodate, ruthenium trichloride * 3H₂O / 1.) carbon tetrachloride, acetonitrile, water, room temperature, 1.5 h; 2.) ether, 3 h

3: 6 h / Irradiation

4: 4-(dimethylamino)pyridine / pyridine / 18 h / Ambient temperature

5: hydrogen / Pd

6: 1.) KOH; 2.) p-toluenesulfonic acid / 1.) EtOH, reflux, 15 min; 2.) benzene,

With dmap; ruthenium trichloride; potassium hydroxide; sodium periodate; hydrogen; toluene-4-sulfonic acid; palladium; In pyridine;

Reference yield:

4-propylbutanolide (105-21-5) → (S)-γ-Propyl-γ-butyrolactone (31323-51-0) + (R)-5-propyl-dihydrofuran-2(3H)-one (88270-38-6)

Guidance literature:

With sodium hydroxide; disodium hydrogenphosphate; porcine pancreating lipase; In diethyl ether; hexane; at 20 ℃; for 120h; pH=7.2;

DOI:10.1016/S0040-4039(02)01268-6

Reference yield:

5-propylfuran-2(5H)-one (57681-53-5) → (S)-γ-Propyl-γ-butyrolactone (31323-51-0) + (R)-5-propyl-dihydrofuran-2(3H)-one (88270-38-6)

Guidance literature:

With Glycine max p83 reductase; NADPH; In phosphate buffer; at 36 ℃; for 5h; pH=7.0; Title compound not separated from byproducts;

DOI:10.1016/j.tetlet.2006.12.126

upstream raw materials:

Acetic acid (S)-1-phenethyl-butyl ester

4-propylbutanolide

4-Hydroxy-heptanoic acid amide

5-propylfuran-2(5H)-one