1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one

Base Information

Chemical Name:1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one
CAS No.:88278-11-9
Molecular Formula:C₂₂H₁₉BrO₃
Molecular Weight:411.295
Hs Code.:
DSSTox Substance ID:DTXSID10557813
Wikidata:Q82439838

Synonyms:88278-11-9;1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one;DTXSID10557813

Suppliers and Price of 1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:410.05176
Heavy Atom Count:26
Complexity:429

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1OCC2=CC=CC=C2)Br)OCC3=CC=CC=C3

Technology Process of 1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one

There total 2 articles about 1-[2,5-Bis(benzyloxy)-4-bromophenyl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 52376-19-9
1-(4-bromo-2,5-dihydroxyphenyl)ethan-1-one

: 100-39-0
benzyl bromide

: 88278-11-9
2,5-dibenzyloxy-4-bromoacetophenone

Guidance literature:: With potassium carbonate; In acetone; Ambient temperature;

Reference yield:

: 25245-34-5
1-bromo-2,5-dimethoxybenzene

: 88278-11-9
2,5-dibenzyloxy-4-bromoacetophenone

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / AlCl₃ / nitrobenzene / 2 h / Ambient temperature

2: 90 percent / BBr₃ / CH₂Cl₂ / 30 min at -70 deg C, then warming to room temp.

3: 71 percent / K₂CO₃ / acetone / Ambient temperature

With aluminium trichloride; boron tribromide; potassium carbonate; In dichloromethane; nitrobenzene; acetone;

Reference yield:

: 88278-11-9
2,5-dibenzyloxy-4-bromoacetophenone

: 88278-20-0
8-benzyloxy-9-bromo-6-methyl-2,6-epoxy-6H-1-benzoxec-3-en-5(2H)-one

Guidance literature:: Multi-step reaction with 3 steps

2: m-chloroperoxybenzoic acid

3: 94 percent / Me₃SiI

With trimethylsilyl iodide; 3-chloro-benzenecarboperoxoic acid;
DOI:10.1039/c39830000896