Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride

Base Information

Chemical Name:Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride
CAS No.:88301-79-5
Molecular Formula:C9H10ClNO2.ClH
Molecular Weight:236.098
Hs Code.:
DSSTox Substance ID:DTXSID40537880

Synonyms:88301-79-5;methyl 2-amino-3-(chloromethyl)benzoate hydrochloride;SCHEMBL6475587;DTXSID40537880;GTXNSRAQVMVQDZ-UHFFFAOYSA-N;Methyl 2-amino-3-(chloromethyl)benzoate--hydrogen chloride (1/1)

Suppliers and Price of Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:235.0166840
Heavy Atom Count:14
Complexity:187

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=CC(=C1N)CCl.Cl

Technology Process of Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride

There total 3 articles about Methyl 2-amino-3-(chloromethyl)benzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.5%

: 92643-51-1
2-Carbomethoxy-6-<(methylsulfinyl)methyl>aniline

: 88301-79-5
2-(Chloromethyl)-6-carbomethoxyanilinium Chloride

Guidance literature:: With hydrogenchloride; In 1,2-dichloro-ethane; at 50 ℃; for 5h;
DOI:10.1021/jo00198a025

Reference yield:

: 92643-45-3
2-Carbomethoxy-6-<(methylthio)methyl>aniline

: 88301-79-5
2-(Chloromethyl)-6-carbomethoxyanilinium Chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 81.6 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 0 °C

2: 95.5 percent / HCl gas / 1,2-dichloro-ethane / 5 h / 50 °C

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/jo00198a025

Reference yield:

: 134-20-3
2-carbomethoxyaniline

: 88301-79-5
2-(Chloromethyl)-6-carbomethoxyanilinium Chloride

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / N-chlorosuccinimide, triethylamine / CH₂Cl₂ / Heating

2: 81.6 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 0 °C

3: 95.5 percent / HCl gas / 1,2-dichloro-ethane / 5 h / 50 °C

With hydrogenchloride; N-chloro-succinimide; triethylamine; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/jo00198a025