134-20-3Relevant articles and documents
Selective synthesis of Rh5 carbonyl clusters within a polyamine dendrimer for chemoselective reduction of nitro aromatics
Maeno, Zen,Mitsudome, Takato,Mizugaki, Tomoo,Jitsukawa, Koichiro,Kaneda, Kiyotomi
, p. 6526 - 6529 (2014)
The selective synthesis of the [Rh5(CO)15] - cluster within the PPI dendrimer was successfully demonstrated. The dendrimer-encapsulated [Rh5(CO)15]- was resistant to decomposition under the catalytic reaction conditions and exhibited extremely high selectivity for the chemoselective reduction of nitro groups of various nitro aromatics with other reducible groups using CO/H2O as a reductant. This journal is the Partner Organisations 2014.
Nickel Boride Reduction of Aryl Nitro Compounds
Seltzman, Herbert H.,Berrang, Bertold D.
, p. 3083 - 3086 (1993)
Nickel boride smoothly reduces aryl nitro compounds to the corresponding anilines in the presence of iodo and ortho carboalkoxy groups in contrast to the problematic reductions by other methods.
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Ogata,Takagi
, p. 5933 (1974)
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Novel VEGFR-2 inhibitors with an N-acylhydrazone scaffold
Pauli, Fernanda P.,Martins, Juliana R.,Paschoalin, Thaysa,Ionta, Marisa,Barbosa, Maria Leticia C.,Barreiro, Eliezer J.
, (2020)
Vascular endothelial growth factor receptor 2 (VEGFR-2) is a tyrosine kinase that mediates a large number of cell responses associated with angiogenesis. The control of the angiogenic pathway in tumorigenesis by the inhibition of VEGFR-2 is considered a p
Reductive carbodiazenylation of nonactivated olefins via aryl diazonium salts
Heinrich, Markus R.,Blank, Olga,Woelfel, Sabrina
, p. 3323 - 3325 (2006)
The reduction of aryl diazonium salts in the presence of nonactivated olefins provides rapid entry to carbodiazenylation products. The regioselective functionalization of double bonds is achieved in a one-pot process starting from aniline derivatives. Car
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Carpenter,Lennon
, p. 664 (1973)
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N-Doped Hierarchical Porous Carbon Embedded Synergistic Bimetallic CoCu NPs with Unparalleled Catalytic Performance
Zhang, Fengwei,Li, Zhihong,Ma, Chunlan,Han, Xu,Dong, Xue,Dong, Zhengping,Zhang, Xian-Ming
, p. 2415 - 2422 (2019)
By virtue of the structural diversity, electronic tunability and synergetic effect, heterogeneous non-noble bimetallic catalysts have demonstrated excellent catalytic performance in Fischer-Tropsch synthesis, biomass conversion and fine chemicals synthesi
ALKYL AND ARYL ISOTHIOCYANATES AS MASKED PRIMARY AMINES
Cho, Cheon-Gyu,Posner, Gary H.
, p. 3599 - 3602 (1992)
Primary and secondary (but not tertiary) alkyl as well as aryl isothiocyanates react rapidly with 4-methyl-1,2-benzenedithiol (1) in methanol at room temperature, releasing the corresponding amines in good yields.This mild and simple procedure for unmasking amines proceeds chemospecifically with isothiocyanates even in the presence of such normally electrophilic and reactive functionalities as carboxylate ester and N-alkylphthalimide.
High-affinity recognition of the human C-reactive protein independent of phosphocholine
Yang, Jie,Gustavsson, Anna-Lena,Haraldsson, Martin,Karlsson, G?ran,Norberg, Thomas,Baltzer, Lars
, p. 4644 - 4654 (2017)
A high-affinity polypeptide conjugate 4-C25L22-DQ, has been developed for the molecular recognition of the human C-reactive protein, CRP, a well-known inflammation biomarker. CRP is one of the most frequently quantified targets in diagnostic applications and a target in drug development. With the exception of antibodies, most molecular constructs take advantage of the known affinity for CRP of phosphocholine that depends on Ca2+ for its ability to bind. 4-C25L22-DQ which is unrelated to phosphocholine binds in the absence of Ca2+ with a dissociation constant of 760 nM, an order of magnitude lower than that of phosphocholine, the KD of which is 5 μM. The small organic molecule 2-oxo-1,2-dihydroquinoline-8-carboxylic acid (DQ) was designed based on the structural similarities between three hits from a set of compounds selected from a building block collection and evaluated with regards to affinity for CRP by NMR spectroscopy. 4-C25L22-DQ was shown in a competition experiment to bind CRP three orders of magnitude more strongly than DQ itself, and in a pull-down experiment 4-C25L22-DQ was shown to extract CRP from human serum. The development of a robust and phosphocholine-independent recognition element provides unprecedented opportunities in bioanalytical applications in vivo and in vitro under conditions where the concentration of Ca2+ ions is low, or where Ca2+ binding agents such as EDTA or heparin are needed to prevent blood coagulation. The identification from a compound library of a small organic molecule and its conjugation to a small set of polypeptides, none of which were previously known to bind CRP, illustrates a convenient and general route to selective high-affinity binders for proteins with dissociation constants in the μM to nM range for which no small molecule ligands are known.
Novel applications of ethyl glyoxalate with the Ugi MCR
Hulme, Christopher,Cherrier
, p. 5295 - 5299 (1999)
This letter describes novel high-yielding solution phase preparations of 1,4-benzodiazepine-2,5-dione, diketopiperazine, ketopiperazine and dihydroquinoxalinone libraries via a UDC (Ugi/de-Boc/cyclization) strategy in combination with ethylglyoxalate. The
Tunable Electrosynthesis of Anthranilic Acid Derivatives via a C-C Bond Cleavage of Isatins
Qian, Peng,Liu, Jiaojiao,Zhang, Yan,Wang, Zhiyong
, p. 16008 - 16015 (2021/07/31)
A facile and direct electrocatalytic C-C bond cleavage/functionalization reaction of isatins was developed. With isatins as the amino-attached C1 sources, a variety of aminobenzoates, and aminobenzamides were synthesized in moderate to good yields under mild conditions.
Development and Application of Efficient Ag-based Hydrogenation Catalysts Prepared from Rice Husk Waste
Unglaube, Felix,Kreyenschulte, Carsten Robert,Mejía, Esteban
, p. 2583 - 2591 (2021/04/09)
The development of strategies for the sustainable management and valorization of agricultural waste is of outmost importance. With this in mind, we report the use of rice husk (RH) as feedstock for the preparation of heterogeneous catalysts for hydrogenation reactions. The catalysts were prepared by impregnating the milled RH with a silver nitrate solution followed by carbothermal reduction. The composition and morphology of the prepared catalysts were fully assessed by IR, AAS, ICP-MS, XPS, XRD and STEM techniques. This novel bio-genic silver-based catalysts showed excellent activity and remarkable selectivity in the hydrogenation of nitro groups in both aromatic and aliphatic substrates, even in the presence of reactive functionalities like halogens, carbonyls, borate esters or nitriles. Recycling experiments showed that the catalysts can be easily recovered and reused multiple times without significant drop in performance and without requiring re-activation.
