N-Fluoro-N-T-butyl-P-toluenesulfonamide

Base Information

Chemical Name:N-Fluoro-N-T-butyl-P-toluenesulfonamide
CAS No.:88303-13-3
Molecular Formula:C11H16FNO2S
Molecular Weight:245.318
Hs Code.:
DSSTox Substance ID:DTXSID10529611
Nikkaji Number:J418.279K
Wikidata:Q82400152

Synonyms:N-FLUORO-N-T-BUTYL-P-TOLUENESULFONAMIDE;88303-13-3;SCHEMBL7020001;DTXSID10529611;VCBBPXLUJNRNPD-UHFFFAOYSA-N;MB69404;N-fluoro-N-t-butyl-p-toluene-sulfonamide;N-tert-Butyl-N-fluoro-4-methylbenzene-1-sulfonamide;88303-15-5

Suppliers and Price of N-Fluoro-N-T-butyl-P-toluenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Fluoro-N-T-butyl-P-toluenesulfonamide

Chemical Property:

PSA：45.76000
LogP:3.74950
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:245.08857809
Heavy Atom Count:16
Complexity:321

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N(C(C)(C)C)F

Technology Process of N-Fluoro-N-T-butyl-P-toluenesulfonamide

There total 3 articles about N-Fluoro-N-T-butyl-P-toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2849-81-2
N-t-butyl-p-toluenesulfonamide

: 88303-13-3
N-(tert-butyl)-N-fluoro-4-methylbenzenesulfonamide

Guidance literature:: N-t-butyl-p-toluenesulfonamide; With sodium hydride; In dichloromethane; mineral oil; at 20 ℃; for 0.5h;

With N-fluorobis(benzenesulfon)imide; In dichloromethane; mineral oil; at 20 ℃; for 4h;
DOI:10.1021/acs.orglett.1c03298

Reference yield: 40.0%

: 88303-13-3
N-(tert-butyl)-N-fluoro-4-methylbenzenesulfonamide

Guidance literature:: With sodium hydride; In dichloromethane; paraffin oil; at 0 ℃; for 0.5h;

With N-fluorobis(benzenesulfon)imide; In dichloromethane; paraffin oil; for 6h;

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 88303-13-3
N-(tert-butyl)-N-fluoro-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0 - 20 °C

2.1: sodium hydride / dichloromethane; mineral oil / 0.5 h / 20 °C

2.2: 4 h / 20 °C

With sodium hydride; triethylamine; In dichloromethane; mineral oil;
DOI:10.1021/acs.orglett.1c03298