N,N'-Bis(2-bromo-4-methylphenyl)urea

Base Information

Chemical Name:N,N'-Bis(2-bromo-4-methylphenyl)urea
CAS No.:88312-99-6
Molecular Formula:C₁₅H₁₄Br₂N₂O
Molecular Weight:398.097
Hs Code.:
DSSTox Substance ID:DTXSID00521063
Wikidata:Q82385316

Synonyms:88312-99-6;N,N'-Bis(2-bromo-4-methylphenyl)urea;DTXSID00521063

Suppliers and Price of N,N'-Bis(2-bromo-4-methylphenyl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N,N'-Bis(2-bromo-4-methylphenyl)urea

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:397.94524
Heavy Atom Count:20
Complexity:310

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)NC(=O)NC2=C(C=C(C=C2)C)Br)Br

Technology Process of N,N'-Bis(2-bromo-4-methylphenyl)urea

There total 4 articles about N,N'-Bis(2-bromo-4-methylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 32315-10-9
bis(trichloromethyl) carbonate

2-bromo-p-toluidine: 583-68-6
2-bromo-p-toluidine

: 88312-99-6
1,3-Bis-(2-bromo-4-methyl-phenyl)-urea

: 71189-13-4
2-Bromo-1-isocyanato-4-methyl-benzene

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 2h; Title compound not separated from byproducts;
DOI:10.1055/s-2003-41019

Reference yield:

: 77791-07-2
N-(2-bromo-4-methylphenyl)-benzamide

: 88312-99-6
1,3-Bis-(2-bromo-4-methyl-phenyl)-urea

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent

2: 1) t-BuLi, LiClO₄; 2) H₂O / 1) THF-pentane, -100 deg C then room temperature; 2) room temperature

With water; tert.-butyl lithium; lithium perchlorate;
DOI:10.1016/S0040-4020(01)91925-8