Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate

Base Information

Chemical Name:Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate
CAS No.:88968-99-4
Molecular Formula:C19H26O5Si
Molecular Weight:362.4922
Hs Code.:

Synonyms:88968-99-4;2,4-Hexadienedioic acid, (4-methoxyphenyl)methyl 2-(trimethylsilyl)ethyl ester, (Z,E)-;Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate

Suppliers and Price of Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate

Chemical Property:

Vapor Pressure:4.02E-08mmHg at 25°C
Boiling Point:445.2°Cat760mmHg
Flash Point:185.3°C
Density:1.058g/cm³
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:362.15495046
Heavy Atom Count:25
Complexity:522

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=C(C=CC(=O)OC)C1=CC=C(C=C1)OC)[Si](C)(C)C
Isomeric SMILES:CCOC(=O)/C(=C(\C=C\C(=O)OC)/C1=CC=C(C=C1)OC)/[Si](C)(C)C

Technology Process of Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate

There total 3 articles about Ethyl methyl (2Z,4E)-3-(4-methoxyphenyl)-2-trimethylsilylhexa-2,4-dienedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 88968-98-3
Mono(p-methoxybenzyl) (E,Z)-Muconate

: 88968-99-4
p-Methoxybenzyl 2-(Trimethylsilyl)ethyl (E,Z)-Muconate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 25 ℃; for 2.5h;
DOI:10.1021/jo00184a021

Reference yield:

: 88968-97-2
p-Methoxybenzyl (Dimethoxyphosphinyl)acetate

: 88968-99-4
p-Methoxybenzyl 2-(Trimethylsilyl)ethyl (E,Z)-Muconate

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / KO-t-Bu / diethyl ether; 2-methyl-propan-2-ol / 3 h / 25 °C

2: 83 percent / Diethyl azodicarboxylate, Ph₃P / tetrahydrofuran / 2.5 h / 25 °C

With potassium tert-butylate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; tert-butyl alcohol;
DOI:10.1021/jo00184a021

Reference yield:

: 105-13-5
4-Methoxybenzyl alcohol

: 88968-99-4
p-Methoxybenzyl 2-(Trimethylsilyl)ethyl (E,Z)-Muconate

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / DCC, DMAP / CH₂Cl₂ / 17 h / 25 °C

2: 76 percent / KO-t-Bu / diethyl ether; 2-methyl-propan-2-ol / 3 h / 25 °C

3: 83 percent / Diethyl azodicarboxylate, Ph₃P / tetrahydrofuran / 2.5 h / 25 °C

With dmap; potassium tert-butylate; dicyclohexyl-carbodiimide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether; dichloromethane; tert-butyl alcohol;
DOI:10.1021/jo00184a021