Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-

Base Information

Chemical Name:Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-
CAS No.:88347-44-8
Molecular Formula:C13H11NO3
Molecular Weight:229.235
Hs Code.:
DSSTox Substance ID:DTXSID70442791
Wikidata:Q82260289

Synonyms:Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-;88347-44-8;SCHEMBL11205340;DTXSID70442791

Suppliers and Price of Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:229.07389321
Heavy Atom Count:17
Complexity:251

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=CC=C2)OCC(=O)O

Technology Process of Acetic acid, [(6-phenyl-2-pyridinyl)oxy]-

There total 2 articles about Acetic acid, [(6-phenyl-2-pyridinyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 337969-46-7
ethyl 2-(6-phenyl-2-pyridyloxy)acetate

: 88347-44-8
2-(6-phenyl-2-pyridyloxy)acetic acid

Guidance literature:: With lithium hydroxide; In 1,2-dimethoxyethane; at 0 ℃; for 1.5h;
DOI:10.1021/jm000410y

Reference yield:

: 19006-82-7
6-phenyl-2-pyridone

: 88347-44-8
2-(6-phenyl-2-pyridyloxy)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / K₂CO₃ / dimethylformamide / 16 h / 20 °C

2: 99 percent / 1N aq. LiOH / 1,2-dimethoxy-ethane / 1.5 h / 0 °C

With lithium hydroxide; potassium carbonate; In 1,2-dimethoxyethane; N,N-dimethyl-formamide;
DOI:10.1021/jm000410y

Reference yield:

: 88347-44-8
2-(6-phenyl-2-pyridyloxy)acetic acid

: (2S)-2-amino-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-3-methylbutan-1-ol hydrochloride

: 337969-42-3
N-[(1S)-2-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-2-hydroxy-1-(methylethyl)ethyl]-2-(6-phenyl-2-pyridyloxy)acetamide

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 14h;
DOI:10.1021/jm000410y