Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate

Base Information

Chemical Name:Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate
CAS No.:88371-30-6
Molecular Formula:C₁₁H₉NO₃
Molecular Weight:203.197
Hs Code.:
DSSTox Substance ID:DTXSID50531410
Wikidata:Q82403253

Synonyms:Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate;88371-30-6;SCHEMBL9293777;DTXSID50531410;2-Oxo-1,2-dihydro-quinoline-8-carboxylic acid methyl ester

Suppliers and Price of Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
Methyl2-hydroxyquinoline-8-carboxylate
1g
$ 1815.33

Alichem
Methyl2-hydroxyquinoline-8-carboxylate
250mg
$ 808.12

Total 3 raw suppliers

Chemical Property of Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate

Chemical Property:

PSA：59.42000
LogP:1.72700
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:203.058243149
Heavy Atom Count:15
Complexity:311

Purity/Quality:: Methyl2-hydroxyquinoline-8-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=CC2=C1NC(=O)C=C2

Technology Process of Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate

There total 4 articles about Methyl 2-oxo-1,2-dihydroquinoline-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: E-methyl 2-(3’-ethoxyprop-2-enoylamido) benzoate

: 88371-30-6
8-methoxycarbonylcarbostyril

Guidance literature:: With hydrogenchloride; In water; at 20 ℃;
DOI:10.1039/c7ob00684e

Reference yield:

: 134-20-3
2-carbomethoxyaniline

: 88371-30-6
8-methoxycarbonylcarbostyril

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 20 °C

2: hydrogenchloride / water / 20 °C

With pyridine; hydrogenchloride; In dichloromethane; water;
DOI:10.1039/c7ob00684e

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 88371-30-6
8-methoxycarbonylcarbostyril

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / dichloromethane

2: pyridine / dichloromethane / 20 °C

3: hydrogenchloride / water / 20 °C

With pyridine; hydrogenchloride; thionyl chloride; In dichloromethane; water;
DOI:10.1039/c7ob00684e