4-amino-5-fluoropentanoic acid

Base Information

• Chemical Name: 4-amino-5-fluoropentanoic acid
• CAS No.: 70960-97-3
• Molecular Formula: C₅H₁₀FNO₂
• Molecular Weight: 135.138
• Mol file: 70960-97-3.mol

Synonyms:4-Amino-5-fluoropentanoicacid; 5-Fluoro-4-aminopentanoic acid; MDL 71109; RMI 72109

Chemical Property of 4-amino-5-fluoropentanoic acid

Chemical Property:

• Vapor Pressure: 0.000945mmHg at 25°C
• Boiling Point: 281.4°C at 760 mmHg
• PKA: 4.22±0.10(Predicted)
• Flash Point: 124°C
• PSA: 63.32000
• Density: 1.173g/cm³
• LogP: 0.84830

Purity/Quality:

99%min ^*data from raw suppliers

4-AMINO-5-FLUOROPENTANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-amino-5-fluoropentanoic acid

There total 2 articles about 4-amino-5-fluoropentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-pyrrolidinon (616-45-5) + 2-chloro-1,1,-trifluorotriethylamine + pyroglutamol (62400-75-3) → 4-fluoromethyl-4-amino-butyric acid (70960-97-3)

Guidance literature:

In tetrahydrofuran; hydrogenchloride; acetonitrile;

Reference yield:

→ 4-fluoromethyl-4-amino-butyric acid (70960-97-3)

Guidance literature:

upstream raw materials:

2-pyrrolidinon

pyroglutamol

Refernces

• 1、 -. "Halomethyl derivatives of gamma-aminobutyric acid and related compounds". . . Retrieved 2008/06/13.