2-Benzylanisole

Base Information

• Chemical Name: 2-Benzylanisole
• CAS No.: 883-90-9
• Molecular Formula: C14H14O
• Molecular Weight: 198.265
• Hs Code.: 2909309090
• Mol file: 883-90-9.mol

Synonyms:1-methoxy-2-(phenylmethyl)benzene;1-benzyl-2-methoxybenzene;2-methoxydiphenylmethane;2-benzyl-1-methoxybenzene;(2-methoxyphenyl)phenylmethane;o-benzyl-methoxybenzene;

Chemical Property of 2-Benzylanisole

Chemical Property:

• Melting Point: 30 °C
• Boiling Point: 123-124 °C(Press: 3 Torr)
• PSA: 9.23000
• Density: 1.028±0.06 g/cm3(Predicted)
• LogP: 3.28600

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Benzylanisole

There total 85 articles about 2-Benzylanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Methoxyphenylboronic acid (5720-06-9) + benzyl chloride (100-44-7) → o-benzyl anisole (883-90-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 100 ℃; for 4h; Inert atmosphere; Large scale reaction;

DOI:10.1002/ejoc.200800544

Reference yield: 98.0%

5-((2-methoxyphenyl)(phenyl)methyl)-2,2-dimethyl-1,3-dioxane-4,6-dione → cycl-isopropylidene malonate (2033-24-1) + o-benzyl anisole (883-90-9)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1002/adsc.201600535

Reference yield: 95.0%

ortho-methoxybenzophenone (2553-04-0) → o-benzyl anisole (883-90-9)

Guidance literature:

With palladium on carbon; hydrogen; In methanol; at 20 ℃; for 16h;

DOI:10.1021/ol500573f

upstream raw materials:

ortho-methoxybenzophenone

o-Methoxybenzyl bromide

o-Benzylphenol

dimethyl sulfate

Downstream raw materials:

o-Benzylphenol

1-(3-benzyl-4-methoxy-phenyl)-ethanone

m-benzylanisole

p-benzylanizole

Refernces

• 1、 Kobayashi, Shū,Koumura, Nagatoshi,Masuda, Koichiro,Okamoto, Yukiko,Onozawa, Shun-Ya. "Development of highly efficient Friedel-Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions". . p. 24424 - 24428. Retrieved 2021/07/29.
• 2、 Guan, Yejun,Hu, Bingwen,Huang, Ju,Jiang, Jingang,Li, Chao,Lu, Kun,Ma, Yanhang,Ren, Li,Wu, Peng,Xu, Hao. "High Ethylene Selectivity in Methanol-to-Olefin (MTO) Reaction over MOR-Zeolite Nanosheets". supporting information. p. 6258 - 6262. Retrieved 2020/02/25.