4-Phenyl-2,3-dihydro-1h-inden-1-one

Base Information

Chemical Name:4-Phenyl-2,3-dihydro-1h-inden-1-one
CAS No.:78383-17-2
Molecular Formula:C15H12O
Molecular Weight:208.26
Hs Code.:
NSC Number:97790
DSSTox Substance ID:DTXSID20294742
Wikidata:Q82034197

Synonyms:4-phenyl-2,3-dihydro-1h-inden-1-one;78383-17-2;4-phenyl-1-indanone;4-phenyl-2,3-dihydroinden-1-one;NSC97790;SCHEMBL7179331;DTXSID20294742;OTSJZOYSLXXFPG-UHFFFAOYSA-N;NSC-97790;AKOS024321579

Suppliers and Price of 4-Phenyl-2,3-dihydro-1h-inden-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4-Phenyl-2,3-dihydro-1h-inden-1-one

Chemical Property:

Vapor Pressure:2.62E-06mmHg at 25°C
Boiling Point:390.6°C at 760 mmHg
Flash Point:173.8°C
Density:1.155g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:208.088815002
Heavy Atom Count:16
Complexity:265

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)C2=CC=CC(=C21)C3=CC=CC=C3

Technology Process of 4-Phenyl-2,3-dihydro-1h-inden-1-one

There total 7 articles about 4-Phenyl-2,3-dihydro-1h-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 15115-60-3
4-bromo-2,3-dihydroinden-1-one

: 98-80-6
phenylboronic acid

: 78383-17-2
4-phenylindan-1-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; In 1,4-dioxane; water; at 80 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.0c03651

Reference yield: 89.0%

: 78383-17-2
4-phenylindan-1-one

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; at 110 ℃; Schlenk technique; Inert atmosphere; Sealed tube;

With dihydrogen peroxide; In ethanol; water; toluene; for 1h;

Reference yield:

: 42287-90-1
3-(3-bromophenyl)propanoic acid

: 78383-17-2
4-phenylindan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 1 h / Reflux

2: aluminum (III) chloride / carbon disulfide / 2.5 h / Reflux

3: tris-imidazolium-stabilized palladium; potassium carbonate / water; toluene / 22 h / 90 °C

With aluminum (III) chloride; thionyl chloride; tris-imidazolium-stabilized palladium; potassium carbonate; In carbon disulfide; water; toluene; 3: Suzuki coupling;
DOI:10.1002/adsc.201100574