beta-Muricholic acid

Base Information

Chemical Name:beta-Muricholic acid
CAS No.:2393-59-1
Molecular Formula:C₂₄H₄₀O₅
Molecular Weight:408.579
Hs Code.:
Nikkaji Number:J367.450I
Wikidata:Q27155232
Metabolomics Workbench ID:36309
Mol file:2393-59-1.mol

Synonyms:3 alpha,6 alpha,7 beta-trihydroxy-5 beta-cholanoic acid;3,6,7-trihydroxy-5-cholanoic acid;alpha-muricholic acid;beta-muricholic acid;hyocholic acid;muricholic acid;muricholic acid, (3alpha,5alpha,6alpha,7alpha)-isomer;muricholic acid, (3alpha,5beta,6alpha,7alpha)-isomer;muricholic acid, (3alpha,5beta,6alpha,7beta)-isomer;muricholic acid, (3alpha,5beta,6beta,7alpha)-isomer;muricholic acid, (3alpha,5beta,6beta,7beta)-isomer;muricholic acid, sodium salt;omega-muricholic acid;trihydroxy-5 alpha-cholanoic acid

Suppliers and Price of beta-Muricholic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
β-Muricholic Acid
1mg
$ 100.00

Sigma-Aldrich
β-Muricholic Acid ≥98% (HPLC)
25mg
$ 699.00

Sigma-Aldrich
β-Muricholic Acid ≥98% (HPLC)
5mg
$ 198.00

Medical Isotopes, Inc.
β-Muricholic Acid
10 mg
$ 2400.00

IsoSciences
β-Muricholic Acid ≥98%
1mg
$ 105.00

Cayman Chemical
β-Muricholic Acid ≥95%
1mg
$ 95.00

Cayman Chemical
β-Muricholic Acid ≥95%
5mg
$ 333.00

Cayman Chemical
β-Muricholic Acid ≥95%
10mg
$ 618.00

American Custom Chemicals Corporation
BETA-MURICHOLIC ACID 95.00%
5MG
$ 454.87

AK Scientific
beta-Muricholicacid
5mg
$ 549.00

Total 15 raw suppliers

Chemical Property of beta-Muricholic acid

Chemical Property:

Vapor Pressure:3.75E-15mmHg at 25°C
Melting Point:226 °C
Boiling Point:565.7°Cat760mmHg
PKA:4.76±0.10(Predicted)
Flash Point:310°C
PSA：97.99000
Density:1.184g/cm³
LogP:3.44870
Storage Temp.:-20°C
Solubility.:DMSO (Slightly), Ethanol (Slightly,Sonicated), Methanol (Slightly), Water (Sligh
XLogP3:3.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:408.28757437
Heavy Atom Count:29
Complexity:637

Purity/Quality:

99%, ^*data from raw suppliers

β-Muricholic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC(=O)O)C1CCC2C1(CCC3C2C(C(C4C3(CCC(C4)O)C)O)O)C
Isomeric SMILES:C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H]([C@H]([C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C
Description β-Muricholic acid (β-MCA) is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.
Uses β-Muricholic Acid is an bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.

Technology Process of beta-Muricholic acid

There total 5 articles about beta-Muricholic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: