Benzamide, N,N-diethyl-2-(2-propenyl)-

Base Information

• Chemical Name: Benzamide, N,N-diethyl-2-(2-propenyl)-
• CAS No.: 88440-83-9
• Molecular Formula: C14H19NO
• Molecular Weight: 217.311
• DSSTox Substance ID: DTXSID00449672
• Nikkaji Number: J754.634C
• Wikidata: Q82269194
• Mol file: 88440-83-9.mol

Synonyms:Benzamide, N,N-diethyl-2-(2-propenyl)-;88440-83-9;2-Allyl-N,N-diethylbenzamide;SCHEMBL5360904;DTXSID00449672

Chemical Property of Benzamide, N,N-diethyl-2-(2-propenyl)-

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 217.146664230
• Heavy Atom Count: 16
• Complexity: 233

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCN(CC)C(=O)C1=CC=CC=C1CC=C

Technology Process of Benzamide, N,N-diethyl-2-(2-propenyl)-

There total 6 articles about Benzamide, N,N-diethyl-2-(2-propenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

allyl methyl carbonate (35466-83-2) + N,N-diethylbenzamide (1696-17-9) → C14H19NO + N,N-Diethyl-2-allylbenzamide (88440-83-9)

Guidance literature:

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; Trimethylacetic acid; In chlorobenzene; at 45 ℃; for 18h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201301165

Reference yield: 80.0%

2-bromo-N,N-diethylbenzamide (76041-86-6) + allyl bromide (106-95-6) + lithium dibutyl(isopropyl)magnesate → N,N-Diethyl-2-allylbenzamide (88440-83-9)

Guidance literature:

2-bromo-N,N-diethylbenzamide; lithium dibutyl(isopropyl)magnesate; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

allyl bromide; With CuCN*2LiCl; In tetrahydrofuran; hexane; at -78 ℃; Further stages.;

DOI:10.1021/jo015597v

Reference yield: 71.0%

N,N-diethylbenzamide (1696-17-9) + allyl bromide (106-95-6) → N,N-Diethyl-2-allylbenzamide (88440-83-9)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; magnesium bromide; In tetrahydrofuran; Other benzamides;

DOI:10.1021/jo00179a001

upstream raw materials:

N,N-diethylbenzamide

allyl bromide

2-bromo-N,N-diethylbenzamide

allyl methyl carbonate

Downstream raw materials:

N,N-diethyl-o-<3-(trimethylsilyl)allyl>benzamide

α-naphthol

2,3-dihydro-2-methyl-1H-inden-1-one

1-amino-naphthalene