N-Benzyl-3,5-bis(trifluoromethyl)aniline

Base Information

Chemical Name:N-Benzyl-3,5-bis(trifluoromethyl)aniline
CAS No.:88450-74-2
Molecular Formula:C15H11F6N
Molecular Weight:319.249
Hs Code.:
DSSTox Substance ID:DTXSID10537418
Nikkaji Number:J3.000.611I
Wikidata:Q82412403

Synonyms:N-Benzyl-3,5-bis(trifluoromethyl)aniline;88450-74-2;DTXSID10537418;QFTNTXCQGYYIEJ-UHFFFAOYSA-N

Suppliers and Price of N-Benzyl-3,5-bis(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-Benzyl-3,5-bis(trifluoromethyl)aniline

Chemical Property:

PSA：12.03000
LogP:5.40930
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:319.07956833
Heavy Atom Count:22
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F

Technology Process of N-Benzyl-3,5-bis(trifluoromethyl)aniline

There total 5 articles about N-Benzyl-3,5-bis(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 100-52-7
benzaldehyde

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 88450-74-2
N-benzyl-3,5-bis(trifluoromethyl)benzenamine

Guidance literature:: With triethylsilane; bismuth(III) chloride; In acetonitrile; at 20 ℃; for 11h; chemoselective reaction; Inert atmosphere; Green chemistry;
DOI:10.1016/j.tetlet.2014.01.132

Reference yield: 95.0%

: N-(3,5-bis(trifluoromethyl)phenyl)-1-phenylmethanimine

: 88450-74-2
N-benzyl-3,5-bis(trifluoromethyl)benzenamine

Guidance literature:: With (4-Ph)Triaz(NHPⁱPr₂)₂Mn(CO)₂Br; potassium tert-butylate; hydrogen; In tetrahydrofuran; at 50 ℃; for 4h; under 15001.5 Torr; chemoselective reaction; Glovebox; Autoclave; Sealed tube;
DOI:10.1021/jacs.9b05024

Reference yield: 95.0%

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 100-51-6,185532-71-2
benzyl alcohol

: 88450-74-2
N-benzyl-3,5-bis(trifluoromethyl)benzenamine

Guidance literature:: With bromopentacarbonylmanganese(I); potassium tert-butylate; N,N-bis-(3-dimethylaminopropyl)amine; In toluene; at 140 ℃; for 18h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1039/c8ob01886c