Technology Process of 3-Cyclohexene-1-acetonitrile, 2-[3-(phenylmethoxy)pentyl]-
There total 10 articles about 3-Cyclohexene-1-acetonitrile, 2-[3-(phenylmethoxy)pentyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium cyanide; sodium iodide;
In
N,N-dimethyl-formamide;
for 24h;
heating;
DOI:10.1021/ja00316a048
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 94 percent / pyridine / 24 h / heating
2: 82 percent / triphenylphosphine, palladium acetate / dioxane / 1 h / Heating
3: 72 percent / hydroquinone / 24 h / 155 °C
4: potassium hydroxide / ethanol; H2O / 16 h / Heating
5: 83 percent / sodium hydride / paraffin; tetrahydrofuran / 1.) r. t., 1 h, 2.) reflux, 3 h
6: lithium aluminium hydride / diethyl ether / 1 h / Heating
7: pyridine / 1 h / Ambient temperature
8: 92 percent / sodium cyanide, sodium iodide / dimethylformamide / 24 h / heating
With
sodium cyanide; potassium hydroxide; lithium aluminium tetrahydride; palladium diacetate; sodium hydride; hydroquinone; triphenylphosphine; sodium iodide;
In
tetrahydrofuran; 1,4-dioxane; pyridine; diethyl ether; ethanol; water; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/ja00316a048
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 83 percent / sodium hydride / paraffin; tetrahydrofuran / 1.) r. t., 1 h, 2.) reflux, 3 h
2: lithium aluminium hydride / diethyl ether / 1 h / Heating
3: pyridine / 1 h / Ambient temperature
4: 92 percent / sodium cyanide, sodium iodide / dimethylformamide / 24 h / heating
With
sodium cyanide; lithium aluminium tetrahydride; sodium hydride; sodium iodide;
In
tetrahydrofuran; pyridine; diethyl ether; N,N-dimethyl-formamide; paraffin;
DOI:10.1021/ja00316a048
