3-Butyn-2-ol, 1-phenoxy-

Base Information

Chemical Name:3-Butyn-2-ol, 1-phenoxy-
CAS No.:88462-64-0
Molecular Formula:C10H10O2
Molecular Weight:162.188
Hs Code.:
DSSTox Substance ID:DTXSID30455327
Nikkaji Number:J445.780C

Synonyms:3-Butyn-2-ol, 1-phenoxy-;1-phenoxybut-3-yn-2-ol;88462-64-0;4-Phenoxy-1-butyn-3-ol;SCHEMBL3147806;DTXSID30455327

Suppliers and Price of 3-Butyn-2-ol, 1-phenoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Butyn-2-ol, 1-phenoxy-

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:162.068079557
Heavy Atom Count:12
Complexity:162

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC(COC1=CC=CC=C1)O

Technology Process of 3-Butyn-2-ol, 1-phenoxy-

There total 11 articles about 3-Butyn-2-ol, 1-phenoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 4301-14-8
acetylenemagnesium bromide

: 2120-70-9
2-phenoxyethanal

: 88462-64-0
3-Hydroxy-4-phenoxy-1-butyne

Guidance literature:

Reference yield:

: 111348-37-9
1-phenoxy-4-(trimethylsilyl)-3-butyn-2-ol

: 88462-64-0
3-Hydroxy-4-phenoxy-1-butyne

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 23 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ol202621g

Reference yield:

: 122-99-6,56257-90-0,9004-78-8
2-Phenoxyethanol

: 88462-64-0
3-Hydroxy-4-phenoxy-1-butyne

Guidance literature:: Multi-step reaction with 3 steps

1.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide; toluene / 2 h / 23 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: -78 - 23 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 23 °C / Inert atmosphere

With n-butyllithium; tetrabutyl ammonium fluoride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; dimethyl sulfoxide; toluene;
DOI:10.1021/ol202621g