2120-70-9

Basic information

• Product Name: CORTEX ALDEHYDE 50 BENZYL ALCOHOL
• Synonyms: phenoxy-acetaldehyd;ASINEX-REAG BAS 02858203;CORTEX ALDEHYDE;CORTEX ALDEHYDE 50 BENZYL ALCOHOL;CORTEX ALDEHYDE 50 P.;2-Phenoxyacetaldehyde;PHENOXY ACETALDEHYDE 50% IN BENZYL ALCOHOL;PHENOXY ACETALDEHYDE
• CAS NO: 2120-70-9
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.15
• EINECS: 218-329-5
• Mol File: 2120-70-9.mol
• Article Data: 44

Chemical Properties

• Melting Point: 38°C
• Boiling Point: 210.42°C (rough estimate)
• Flash Point: 92.4°C
• Appearance: /
• Density: 1.1150 (rough estimate)
• Vapor Pressure: 0.113mmHg at 25°C
• Refractive Index: 1.5090 (estimate)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: CORTEX ALDEHYDE 50 BENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: CORTEX ALDEHYDE 50 BENZYL ALCOHOL(2120-70-9)
• EPA Substance Registry System: CORTEX ALDEHYDE 50 BENZYL ALCOHOL(2120-70-9)

Safety Data

• Hazardous Substances Data: 2120-70-9(Hazardous Substances Data)

Usage

Occurrence

Has apparently not been reported to occur in nature.

Preparation

From phenol in weak aqueous alkali with monochloroacetaldehyde dimethyl acetal to yield the acetal which is then hydrolysed.

InChI:InChI=1/C8H8O2/c9-6-7-10-8-4-2-1-3-5-8/h1-6H,7H2

Upstream product

• 538-43-2 3-phenoxy-1,2-propanediol 
• 546-67-8 lead(IV) tetraacetate 
• 71-43-2 benzene 
• 7681-38-1 sodium hydrogen sulfate 
• 79-37-8 oxalyl dichloride 
• 122-99-6 2-Phenoxyethanol 
• 67-68-5 dimethyl sulfoxide 
• 591-50-4 iodobenzene 
• 3613-97-6 N,N-Diethyl-phenoxyacetamide 
• 108-95-2 phenol 
• 1746-13-0 allyl phenyl ether 
• 3598-14-9 phenoxyacetonitrile 
• 139-02-6 sodium phenoxide 
• 122-59-8 2-phenoxyacetic acid 

Downstream Products

• 75933-70-9 4-phenoxy-trans-crotonic acid 
• 850857-03-3 2-(2,2-dicyano-1-phenoxymethyl-ethyl)-acetoacetic acid ethyl ester 
• 271-89-6 1-benzofurane 
• 192652-08-7 C₂₂H₂₂O₃ 
• 917-23-7 5,15,10,20-tetraphenylporphyrin 
• 5421-29-4 phenoxyacetic acid 2-phenoxyethyl ester 
• 7695-63-8 (+/-)-1-isopropylamino-3-phenoxypropan-2-ol 
• 29638-63-9 1-(butylamino)-3-phenoxypropan-2-ol 
• 64980-40-1 1-(N-tert-butyl)amino-3-phenoxy-2-propanol 
• 53673-51-1 1-benzylamino-3-phenoxy-propan-2-ol 
• 52752-55-3 (Z)-1,4-di(phenoxy)but-2-ene 
• 15779-52-9 (E)-1,4-diphenoxybut-2-ene 
• 112243-65-9 (S)-2-hydroxy-3-phenoxypropylamine 
• 106985-59-5 phenoxyacetaldehyde cyanohydrin acetate 

Relevant articles and documents

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COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF

It is related to compounds used as autophagy modulators and a method for preparing and using the same, specifically providing a compound of general formula (I), or pharmaceutically acceptable salts thereof, which is a type of autophagy modulators, particularly mammalian ATG8 homologues modulators.

Gold(III)-Catalyzed Intermolecular Oxidation-Cyclization of Ynones: Access to 4-Substituted Chroman-3-ones

A synthesis of 4-substituted chroman-3-one derivatives has been developed through a gold(III) catalyzed oxidation-cyclization of ynones in good to excellent yield using easily prepared substrates. A broad range of synthetically useful functional groups (halide, alkene, alkyne, phenolic hydroxyl) were tolerated. Further application of this method paves a new way to prepare the skeleton of oblarotenoids. A cascade oxidative cyclization for construction of pyrano[2,3-c]chromen-1(5H)-one derivatives is also presented. (Figure presented.).