Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate

Base Information

Chemical Name:Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate
CAS No.:88469-73-2
Molecular Formula:C₁₃H₁₁NO₃S
Molecular Weight:261.301
Hs Code.:
DSSTox Substance ID:DTXSID00519001
Wikidata:Q82381901

Synonyms:88469-73-2;Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate;DTXSID00519001

Suppliers and Price of Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:261.04596439
Heavy Atom Count:18
Complexity:305

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N=C(S1)C2=CC=CC=C2)C=O

Technology Process of Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate

There total 7 articles about Ethyl 4-formyl-2-phenyl-1,3-thiazole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41980-85-2
2-Phenyl-4-chlormethyl-thiazol-5-yl-carbonsaeure

: 88469-73-2
5-Ethoxycarbonyl-4-formyl-2-phenyl-thiazol

Guidance literature:: Multi-step reaction with 5 steps

1: SOCl₂ / 1 h / Heating

2: 0.08 h / Heating

3: water / 4 h / Heating

4: conc. H₂SO₄ / Heating

5: K₂Cr₂O₇ / acetic acid / 1 h

With potassium dichromate; thionyl chloride; sulfuric acid; water; In acetic acid;
DOI:10.1002/ardp.19833161208

Reference yield:

: 88469-68-5
5-Chlorformyl-4-chlormethyl-2-phenyl-thiazol

: 88469-73-2
5-Ethoxycarbonyl-4-formyl-2-phenyl-thiazol

Guidance literature:: Multi-step reaction with 4 steps

1: 0.08 h / Heating

2: water / 4 h / Heating

3: conc. H₂SO₄ / Heating

4: K₂Cr₂O₇ / acetic acid / 1 h

With potassium dichromate; sulfuric acid; water; In acetic acid;
DOI:10.1002/ardp.19833161208

Reference yield:

: 83983-12-4
4-Chlormethyl-5-ethoxycarbonyl-2-phenyl-thiazol

: 88469-73-2
5-Ethoxycarbonyl-4-formyl-2-phenyl-thiazol

Guidance literature:: Multi-step reaction with 3 steps

1: water / 4 h / Heating

2: conc. H₂SO₄ / Heating

3: K₂Cr₂O₇ / acetic acid / 1 h

With potassium dichromate; sulfuric acid; water; In acetic acid;
DOI:10.1002/ardp.19833161208