Minozac free base

Base Information

Chemical Name:Minozac free base
CAS No.:886208-65-7
Molecular Formula:C19H20N6
Molecular Weight:332.408
Hs Code.:
UNII:FLX2OWQ78O
ChEMBL ID:CHEMBL232211
DSSTox Substance ID:DTXSID80467910
Wikidata:Q27278058

Synonyms:2-(4-(4-methyl-6-phenylpyridazin-3-yl)piperazin-1-yl)pyrimidine;MW-151;MW01-2-151SRM

Suppliers and Price of Minozac free base

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Minozac free base

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:332.17494466
Heavy Atom Count:25
Complexity:399

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NN=C1N2CCN(CC2)C3=NC=CC=N3)C4=CC=CC=C4
Recent ClinicalTrials:MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases

Technology Process of Minozac free base

There total 9 articles about Minozac free base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 28657-39-8
3-chloro-4-methyl-6-phenylpyridazine

: 20980-22-7
N-(2-pyridinyl)piperazine

: 886208-65-7
Minozac

Guidance literature:: In butan-1-ol; at 130 ℃; for 60h; Product distribution / selectivity; Sealed vessel;

Reference yield: 63.0%

: 886208-70-4
4-chloro-6-phenyl-3-(4-pyrimidin-2-yIpiperazin-1-yl)pyridazine

: 13061-96-6
dihydroxy-methyl-borane

: 886208-65-7
Minozac

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; silver(l) oxide; In tetrahydrofuran; dichloromethane; at 120 ℃; for 18.5h;
DOI:10.1016/j.bmcl.2006.10.028

Reference yield: 50.0%

: 1395922-75-4
C₁₃H₁₅ClN₆

: 98-80-6
phenylboronic acid

: 886208-65-7
Minozac

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,2-dimethoxyethane; at 110 ℃; for 48h; Inert atmosphere;
DOI:10.1021/ml3001769